No Association Between Tea Consumption and Risk of Renal Cell Carcinoma: A Meta-analysis of Epidemiological Studies

Hu, Zhenghui; Lin, Yiwei; Xu, Xin; Chen, Hong; Mao, Yuliang; Wu, Jian; Xu, Xianglai; Zhu, Yi; Li, Shiqi; Zheng, Xiangyi; Xie, Liping

doi:10.7314/apjcp.2013.14.3.1691

Cited by 11 publications

(8 citation statements)

References 29 publications

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“…There was no obvious significant association of high consumption of tea with breast cancer, non‐melanoma skin cancer, bladder cancer, prostate cancer, pancreatic cancer, colorectal cancer, renal cell cancer, laryngeal cancer, and pharyngeal cancer . Consistent results were obtained for bladder cancer, laryngeal cancer, liver cancer, pancreatic cancer, and oral cancer checking the concordance, direction, and significance of the meta‐analyses of the same exposure and cancer outcome.…”

Section: Resultsmentioning

confidence: 99%

Tea Consumption and Health Outcomes: Umbrella Review of Meta‐Analyses of Observational Studies in Humans

Zhuang

et al. 2019

Molecular Nutrition Food Res

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Scope The aim of this article is to conduct an umbrella review to study the strength and validity of associations between tea consumption and diverse health outcomes. Methods and results Meta‐analyses of observational studies examining associations between tea consumption and health outcomes in all human populations and settings are screened. The umbrella review identifies 96 meta‐analyses with 40 unique health outcomes. Tea consumption shows greater benefits than harm to health in this review. Dose–response analyses of tea consumption indicates reduced risks of total mortality, cardiac death, coronary artery disease, stroke, and type 2 diabetes mellitus with increment of two to three cups per day. Beneficial associations are also found for several cancers, skeletal, cognitive, and maternal outcomes. Harmful associations are found for esophageal and gastric cancer when the temperature of intake is more than 55–60 °C. Conclusion Tea consumption, except for very hot tea, seems generally safe at usual levels of intake, with summary estimates indicating the largest reduction for diverse health outcomes at two to three cups per day. Generally, tea consumption seems more beneficial than harmful in this umbrella review. Randomized controlled trials are further needed to understand whether the observed associations are causal.

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Section: Resultsmentioning

confidence: 99%

Tea Consumption and Health Outcomes: Umbrella Review of Meta‐Analyses of Observational Studies in Humans

Zhuang

et al. 2019

Molecular Nutrition Food Res

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“…Several systematic reviews and meta-analyses conducted subsequently also reported inconsistent results for the potential association of coffee or tea on certain types of cancers such as prostate, lung, colorectal, oesophageal, renal, or breast cancers. Indeed, whilst some of the studies reported inverse associations for tea or coffee (e.g., coffee and liver or prostate cancers, tea and lung cancer) [ 8 , 9 , 10 , 11 , 12 , 13 ], others did not observe any significant adverse or potential protective effects of such beverages [ 14 , 15 , 16 , 17 , 18 , 19 ].…”

Section: Introductionmentioning

confidence: 99%

Coffee and Tea Consumption and the Contribution of Their Added Ingredients to Total Energy and Nutrient Intakes in 10 European Countries: Benchmark Data from the Late 1990s

et al. 2018

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Background: Coffee and tea are among the most commonly consumed nonalcoholic beverages worldwide, but methodological differences in assessing intake often hamper comparisons across populations. We aimed to (i) describe coffee and tea intakes and (ii) assess their contribution to intakes of selected nutrients in adults across 10 European countries. Method: Between 1995 and 2000, a standardized 24-h dietary recall was conducted among 36,018 men and women from 27 European Prospective Investigation into Cancer and Nutrition (EPIC) study centres. Adjusted arithmetic means of intakes were estimated in grams (=volume) per day by sex and centre. Means of intake across centres were compared by sociodemographic characteristics and lifestyle factors. Results: In women, the mean daily intake of coffee ranged from 94 g/day (~0.6 cups) in Greece to 781 g/day (~4.4 cups) in Aarhus (Denmark), and tea from 14 g/day (~0.1 cups) in Navarra (Spain) to 788 g/day (~4.3 cups) in the UK general population. Similar geographical patterns for mean daily intakes of both coffee and tea were observed in men. Current smokers as compared with those who reported never smoking tended to drink on average up to 500 g/day more coffee and tea combined, but with substantial variation across centres. Other individuals’ characteristics such as educational attainment or age were less predictive. In all centres, coffee and tea contributed to less than 10% of the energy intake. The greatest contribution to total sugar intakes was observed in Southern European centres (up to ~20%). Conclusion: Coffee and tea intake and their contribution to energy and sugar intake differed greatly among European adults. Variation in consumption was mostly driven by geographical region.

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“…We identified the following exposures associated with the incidence of RCC: healthy dietary pattern [ 64 ], unhealthy/Western pattern [ 64 ], drinking pattern [ 64 ], fish [ 65 ], total fat [ 87 ], sweetened carbonated beverage [ 66 ], beer [ 67 ], wine [ 67 ], spirits [ 67 ], riboflavin [ 68 ], vitamin B6 [ 68 ], folate [ 68 ], vitamin B12 [ 68 ], saturated fat [ 87 ], methionine [ 68 ], choline [ 68 ], betaine [ 68 ], all meats [ 15 ], tea [ 69 ], fruit fiber [ 70 ], vegetable fiber [ 70 ], cereal fiber [ 70 ], legume fiber [ 70 ], dietary inflammatory index [ 71 ], vitamin C [ 72 ], seafood [ 16 ], animal fat [ 16 ], cholesterol [ 16 ], total protein [ 87 ], animal protein [ 87 ], plant fat [ 16 ], plant protein [ 87 ], sweetened beverages (including artificially sweetened beverages and sugar-sweetened beverages) [ 73 ], polyunsaturated fat [ 87 ], vitamin E [ 74 ], coffee [ 75 ], vitamin D [ 76 ], dietary nitrate [ 77 ], dietary nitrite [ 77 ], glycemic index [ 78 ], glycemic load [ 78 ], monounsaturated fat [ 87 ], dietary fiber [ 78 ], alcohol (light) [ 79 ], alcohol (moderate) [ 79 ], alcohol (heavy) [ 79 ], alcohol (any) [ 79 ], vegetables [ 80 ], fruit [ 80 ], red meat [ 17 ], processed meat [ 17 ], cruciferous vegetables [ 81 ], poultry [ 15 , 16 ], fruit and non-starchy vegetables [ 87 ], non-starchy vegetables [ 87…”

Section: Resultsmentioning

confidence: 99%

The role of diet in renal cell carcinoma incidence: an umbrella review of meta-analyses of observational studies

Liao

Fang

Gou

et al. 2022

BMC Med

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Background Evidence associating diet with the incidence of renal cell carcinoma (RCC) is inconclusive. We aimed to summarize evidence associating dietary factors with RCC incidence and assess the strength and validity of this evidence. Methods We conducted an umbrella review of systematic reviews or meta-analyses (SRoMAs) that assessed the association between diet and RCC incidence. Through April 2021, PubMed, Web of Science, Embase, The Cochrane Library, Scopus, and WCRF were searched. Two independent reviewers selected studies, extracted data, and appraised the quality of SRoMAs. According to credibility assessment criteria, evidence can be divided into five categories: convincing (class I), highly suggestive (class II), suggestive (class III), weak (class IV), and nonsignificant (class V). Results Twenty-nine meta-analyses were obtained after screening. After excluding 7 overlapping meta-analyses, 22 meta-analyses including 502 individual studies and 64 summary hazard ratios for RCC incidence were included: dietary patterns or dietary quality indices (n = 6), foods (n = 13), beverages (n = 4), alcohol (n = 7), macronutrients (n =15), and micronutrients (n =19). No meta-analyses had high methodological quality. Five meta-analyses exhibited small study effects; one meta-analysis showed evidence of excess significance bias. No dietary factors showed convincing or highly suggestive evidence of association with RCC in the overall analysis. Two protective factors had suggestive evidence (vegetables (0.74, 95% confidence interval 0.63 to 0.86) and vitamin C (0.77, 0.66 to 0.90)) in overall analysis. One protective factor had convincing evidence (moderate drinking (0.77, 0.70 to 0.84)) in Europe and North America and one protective factor had highly suggestive evidence (cruciferous vegetables (0.78, 0.70 to 0.86)) in North America. Conclusions Although many meta-analyses have assessed associations between dietary factors and RCC, no high-quality evidence exists (classes I and II) in the overall analysis. Increased intake of vegetables and vitamin C is negatively associated with RCC risk. Moderate drinking might be beneficial for Europeans and North Americans, and cruciferous vegetables might be beneficial to North Americans, but the results should be interpreted with caution. More researches are needed in the future. Trial registration PROSPERO CRD42021246619

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No Association Between Tea Consumption and Risk of Renal Cell Carcinoma: A Meta-analysis of Epidemiological Studies

Cited by 11 publications

References 29 publications

Tea Consumption and Health Outcomes: Umbrella Review of Meta‐Analyses of Observational Studies in Humans

Tea Consumption and Health Outcomes: Umbrella Review of Meta‐Analyses of Observational Studies in Humans

Coffee and Tea Consumption and the Contribution of Their Added Ingredients to Total Energy and Nutrient Intakes in 10 European Countries: Benchmark Data from the Late 1990s

The role of diet in renal cell carcinoma incidence: an umbrella review of meta-analyses of observational studies

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