Magnetic resonance (MR) is a powerful new imaging modality which has recently become competitive with x-ray computed tomography (CT) for imaging of the central nervous system (CNS). The advantages of MR include lack of ionizing radiation and the necessity to use iodinated contrast. MR is able to provide images directly in the transaxial, coronal, and sagittal planes. When appropriate pulsing sequences are used, MR can be more sensitive than CT in the detection of early disease associated with increased water content. Included in this category are multiple sclerosis, early infarcts, small tumors, and inflammatory lesions. MR is superior to CT in the posterior and middle fossae due to the beam hardening artifacts which degrade the older modality. In the cord, MR is particularly useful in the evaluation of myelopathies, e.g., syringomyelia, spinal dysraphism, and intramedullary tumors.Due to its increased sensitivity in the detection of early disease, MR should generally be used as the initial screening procedure in the evaluation of suspected intracranial disease or disease of the cord. Current limitations of MR include: longer single slice imaging times, thicker slices, general lack of available contrast agents to define blood-brain barrier break-down, and the inability to image calcification and cortical bone. Patients on cardiac monitors or on respirators and those with intracranial aneurysm clips and cardiac pacemakers are currently excluded from MR imaging.