Nitrous oxide does not consistently reduce isoflurane requirement in cats

A systematic review of sevoflurane and isoflurane minimum alveolar concentration in domestic cats

“…; Imai et al. ). Studies which reported using a nonrebreathing system reported a significantly higher isoflurane MAC value compared with studies which reported using a rebreathing system (1.9% versus 1.61%, p < 0.02).…”

“…Three studies did not report what type of equipment was used to measure inhalant concentrations (Imai et al. ; Lamont et al. ; Escobar et al.…”

“…), in the fourth study, eight males and four females were used (Imai et al. ), and in the fifth study, four males and three females were used (Zwijnenberg et al. ).…”

“…The effect of sex on the MAC of isoflurane was explored in one study, which documented an isoflurane MAC of 2.06 ± 0.08% for four females and 1.86 ± 0.22% for eight males, which did not appear to be different (Imai et al. ).…”

The effects of ketamine on the minimum alveolar concentration of isoflurane in cats

“…The method of measurement of MAC used in this study has been described previously (Ilkiw et al., 1997, 2002; Imai et al., 2002; Pypendop & Ilkiw, 2005b). Values for the MAC of isoflurane in the cat have ranged from 1.2 ± 0.13% to 2.21 ± 0.17% (Steffey & Howland, 1977; Ilkiw et al., 1997, 2002; March & Muir, 2003; Barter et al., 2004; Yackey et al., 2004; Lamont et al., 2005; Pypendop & Ilkiw, 2005b), so the values determined in this study are within this range.…”