“…It seems thus possible that an expansion of muscle protein mass would occur very slowly and might continue for periods in excess of 50 d. Fat-free mass was not reported, but urinary creatinine, as a measure of muscle mass, increased signi®cantly by 4% (Oddoye & Margen,1979), which is consistent with the 1%ad increase in muscle protein for 50 d predicted from the N balance. However, other studies have not detected signi®cant changes in urinary creatinine excretion, fat-free mass, or other measures of protein deposition (Fisher et al, 1967;Cheng et al, 1978;Tarnapolsky et al, 1992). Even during 12 weeks of resistance training in older subjects (Campbell et al, 1995) or 1 month of strength training in young adults (Lemon et al, 1992), no differences due to higher dietary protein could be detected in fat-free mass, urinary creatinine, and muscle size (by computerized tomography) and composition.…”