Nitrogen Mustard in the Palliation of Lung Cancer

Bass, Bob

doi:10.1136/bmj.1.5173.617

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1961

1979

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Cited by 16 publications

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“…It has often been stated that nitrogen mustard does not prolong life in bronchial carcinoma (Bass, 1960). Grenville-Mathers and Trenchard (1964) were unable to show that patients treated with cyclophosphamide survived two months longer than a control group.…”

Section: Discussionmentioning

confidence: 98%

“…Lynch, Ware, and Gaensler (1950), Kent and Reh (1950), Levine andWeisberger (1955), Hatch, Bradford, andOchsner (1956), and Bass (1960) have described their experience with this cytotoxic agent and have reported symptomatic improvement in many patients, but little or no prolongation of life. Since 1958, when cyclophosphamide was synthesized, it has been widely used for malignant disease, including lung cancer, both palliatively in advanced inoperable disease (Spear and Patno, 1962;Braun-Wotke, 1963), and as cover for operation in patients with less-advanced disease (Poulsen, 1962(Poulsen, , 1963.…”

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confidence: 99%

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