Nitrile aus Aldehyden und 4‐Aminocyclopenta[e]‐1,2,4‐triazinen

Abstract

Aldehyde werden unter Verwendung von 4‐Amino‐4,6‐dihydro‐1H‐cyclopenta[e]‐1,2,4‐triazin‐5,

The Chemistry of N-Hydroxyamidoximes, N-Aminoamidoximes, and Hydrazidines

“…69 In addition, methylhydrazidine 51a was used for the preparation of 3-methylpyrrolo[1,2]-1,2,4,5-tetrazine 118 via cyclization with cis-or trans-2,5-dimethoxy-2,5-dihydrofuran 111 (Scheme 34). 70 Neunhoeffer et al also prepared tetrazine derivatives 120 and 122 by the reaction of benzylhydrazidine 61 with anhydrides 106b and 119 (Scheme 35). 64 6.2.9.…”

“…The reaction of hydrazidine 51 with benzil 77 gives 4-amino-1,2,4-triazines 83 , preferentially. However, reaction with 4,4-dimethyl-1,2-cyclopentandione 78 gave octaaza[14]-annulen 84 . The reaction of benzylhydrazidine 51 with 2-hydroxy-4,4-dimethyl-2-cyclopenten-1-one 79 gave 4-amino-1,2,4-triazines 85 , tetrahydrotetrazine 86 , and octaaza[14]-annulen 87 (Scheme ) …”

“…Methylhydrazidine 51a reacts with 2,3-dihydroxycyclo-pentadiene-1,4-dicarboxylate-dimethylester 123 to give 4-amino-4,6-dihydro-3-methyl-1 H -cyclopenta[ e ]1,2,4-triazin-5,7-dicarboxylester 124 (Scheme , Table ) …”