Nitric oxide, chronic iron and copper overloads and regulation of redox homeostasis in rat liver

Lairion, Fabiana; Saporito-Magriñá, Christian; Musacco-Sebio, Rosario; Fuda, Julián; Torti, Horacio; Repetto, Marisa G.

doi:10.1007/s00775-021-01908-1

Cited by 3 publications

(1 citation statement)

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“…Subsequently, the results were read at 240 nm against a control cuvette containing enzyme solution without H 2 O 2 phosphate buffer. The optical density normally dropped (from 0.45 to 0.40) and was recorded (Lairion et al, 2022).…”

Section: Measurement Of Catalasementioning

confidence: 99%

Potential effects of noni (Morinda citrifolia L.) fruits extract against obsessive-compulsive disorder in marble burying and nestlet shredding behavior mice models

Jeyabalan

Bala

Kavimani³

et al. 2022

Front. Pharmacol.

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Obsessive-compulsive disorder (OCD) is a chronic and complex psychiatric disorder that usually includes both obsessions and compulsions. Morinda citrifolia L. (Noni) is a functional food and it is a well-known plant due to its potential therapeutic effects on human health in many disorders including neurological and neurodegenerative diseases. The purpose of this study was to evaluate the potential effect of M. citrifolia fruits extract (MCFE) against obsessive-compulsive disorder using the marble burying and nestlet shredding behavior mice models. In addition, brain neurotransmitters such as dopamine (DA), serotonin and noradrenaline (NA) were also assessed. Five mice were placed in each of the different groups, and the treatment was given to the animals for a period of 15 days. The marble burying test was evaluated for 30 min on days 1, 7, and 14 while the nestlet shredding test was evaluated for 60 min on days 2, 8, and 15. Treatments with MCFE (100 and 200 mg/kg, p.o.) significantly improved in both behavior tasks when compared to the control group. In addition, diazepam (2 mg/kg, i.p.) and fluoxetine (15 mg/kg,

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Section: Measurement Of Catalasementioning

confidence: 99%