NIR-responsive 5-Fluorouracil delivery using polydopamine coated polygonal CuS nanoplates for synergistic chemo-photothermal therapy on breast cancer

Pal, Kaushik; Mahato, Priya; Singh, Swati; Roy, Partha

doi:10.1016/j.jddst.2022.104092

Cited by 7 publications

(4 citation statements)

References 43 publications

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“…The strong absorption of near‐infrared light (700–1000 nm) by PDA is the basis of PTT 53 . Numerous researches 54–57 have demonstrated that PDA has good biocompatibility and antimicrobial properties when irradiated at 808 nm.…”

Section: Methodsmentioning

confidence: 99%

“…The strong absorption of near-infrared light (700-1000 nm) by PDA is the basis of PTT. 53 Numerous researches [54][55][56][57] have demonstrated that PDA has good biocompatibility and antimicrobial properties when irradiated at 808 nm. Cur can produce ROS under 405 nm light irradiation, effectively killing S. aureus and E. coli, two highly pathogenic bacteria.…”

Section: The Selection Of the Specific Light Wavelengthsmentioning

confidence: 99%

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Polydopamine‐curcumin coating of titanium for remarkable antibacterial activity via synergistic photodynamic and photothermal properties

Guo,

Li,

Zhang

et al. 2023

Photochem & Photobiology

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Combined photothermal therapy (PTT) and photodynamic therapy (PDT) has emerged as a novel and effective antibacterial strategy. In order to endow titanium (Ti) with antibacterial properties, the Ti‐PDA‐Cur composite was prepared using the excellent adhesion properties of polydopamine (PDA) to load curcumin (Cur) on the surface of Ti. The Ti‐PDA‐Cur coating can produce singlet oxygen (1O2) and heat under 405 + 808 nm light irradiation, which can effectively kill Staphylococcus aureus and Escherichia coli. Moreover, the cytotoxicity and hemolysis rate of Ti‐PDA‐Cur were low, indicating its good biocompatibility. Therefore, this study provided a new strategy for the development of new Ti implants.

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Section: Methodsmentioning

confidence: 99%

Section: The Selection Of the Specific Light Wavelengthsmentioning

confidence: 99%

Polydopamine‐curcumin coating of titanium for remarkable antibacterial activity via synergistic photodynamic and photothermal properties

Guo,

Li,

Zhang

et al. 2023

Photochem & Photobiology

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“…In recent years, photothermal therapy with photothermal conversion characteristics has become a hot topic, and the noninvasive, unique location and time specificity of photothermal therapy are its significant advantages. [15,16] Transition-metal dichalcogenide is widely used in biomedicine due to its high photothermal absorption in the near infrared region. Among them, tungsten disulfide (WS 2 ) and molybdenum disulfide (MoS 2 ) have significant effects in our previous anti-tumor research by selective photothermal ablation of cancer cells.…”

Section: Introductionmentioning

confidence: 99%

Macrophage Membrane‐Modified MoS₂ Quantum Dots as a Nanodrug for Combined Multi‐Targeting of Alzheimer's Disease

Qi,

Li,

et al. 2023

Adv Healthcare Materials

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The complex pathological mechanism of Alzheimer's disease (AD) limits the efficacy of simple drug therapy, and drugs are difficult to penetrate the blood‐brain barrier (BBB). Therefore, it is a breakthrough to enhance the therapeutic effect of AD by rationally using multiple therapeutic strategies to inhibit multiple pathological targets. In this study, macrophage membrane (MM) with active targeting inflammation function was used to functionalize molybdenum disulfide quantum dots (MoS2 QDs) with the properties of elimination of reactive oxygen species (ROS) and anti‐Aβ1‐42 deposition to form the nano drug (MoS2 QDs/MM), and play the role of multi‐target combined therapy with NIR. The results showed that MoS2 QDs/MM has a targeted therapeutic effect on ROS elimination and anti‐deposition of Aβ1‐42. In addition, the combined therapy group effectively reduced Aβ1‐42 mediated cytotoxicity. The modification of MM could effectively target the brain, and NIR irradiation could actively increase the cross of BBB of materials. In vivo behavioral study also showed that APP/PS1 mice in the combined treatment group showed the similar exploration desire and learning ability to mice in the group of WT. MoS2 QDs/MM is an excellent nano drug with multiple effects, which has advantages in the field of neurological diseases with crisscross pathogenesis.This article is protected by copyright. All rights reserved

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“…Photothermal therapy (PTT) can be applied for hypoxic tumor treatment because it does not depend on the oxygen level [ 9 , 10 , 11 ]. PTT utilizes the increased sensitivity of cancer cells to temperatures rising up to 41–47 °C [ 12 , 13 , 14 , 15 , 16 ]. Local hyperthermia was approved for cancer treatment and radiosensitization [ 17 ].…”

Section: Introductionmentioning

confidence: 99%

Targeted PLGA–Chitosan Nanoparticles for NIR-Triggered Phototherapy and Imaging of HER2-Positive Tumors

Kotelnikova,

Shipunova,

Deyev

2023

Pharmaceutics

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Targeted medicine uses the distinctive features of cancer cells to find and destroy tumors. We present human epidermal growth factor receptor 2 (HER2)-targeted PLGA–chitosan nanoparticles for cancer therapy and visualization. Loading with two near-infrared (NIR) dyes provides imaging in the NIR transparency window and phototherapy triggered by 808 nm light. Nile Blue (NB) is a biocompatible solvatochromic NIR dye that serves as an imaging agent. Laser irradiation of IR-780 dye leads to a temperature rise and the generation of reactive oxygen species (ROS). Resonance energy transfer between two dyes allows visualization of tumors in a wide range of visible and IR wavelengths. The combination of two NIR dyes enables the use of nanoparticles for diagnostics only or theranostics. Modification of poly(lactic-co-glycolic acid) (PLGA)–chitosan nanoparticles with trastuzumab provides an efficient nanoparticle uptake by tumor cells and promotes more than sixfold specificity towards HER2-positive cells, leading to a synergistic anticancer effect. We demonstrate optical imaging of the HER2-positive mouse mammary tumor and tumor-specific accumulation of PLGA–IR-780–NB nanoparticles in vivo after intravenous administration. We managed to achieve almost complete suppression of the proliferative activity of cells in vitro by irradiation with an 808 nm laser with a power of 0.27 W for 1 min at a concentration at which nanoparticles are nontoxic to cells in the dark.

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NIR-responsive 5-Fluorouracil delivery using polydopamine coated polygonal CuS nanoplates for synergistic chemo-photothermal therapy on breast cancer

Cited by 7 publications

References 43 publications

Polydopamine‐curcumin coating of titanium for remarkable antibacterial activity via synergistic photodynamic and photothermal properties

Polydopamine‐curcumin coating of titanium for remarkable antibacterial activity via synergistic photodynamic and photothermal properties

Macrophage Membrane‐Modified MoS₂ Quantum Dots as a Nanodrug for Combined Multi‐Targeting of Alzheimer's Disease

Targeted PLGA–Chitosan Nanoparticles for NIR-Triggered Phototherapy and Imaging of HER2-Positive Tumors

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NIR-responsive 5-Fluorouracil delivery using polydopamine coated polygonal CuS nanoplates for synergistic chemo-photothermal therapy on breast cancer

Cited by 7 publications

References 43 publications

Polydopamine‐curcumin coating of titanium for remarkable antibacterial activity via synergistic photodynamic and photothermal properties

Polydopamine‐curcumin coating of titanium for remarkable antibacterial activity via synergistic photodynamic and photothermal properties

Macrophage Membrane‐Modified MoS2 Quantum Dots as a Nanodrug for Combined Multi‐Targeting of Alzheimer's Disease

Targeted PLGA–Chitosan Nanoparticles for NIR-Triggered Phototherapy and Imaging of HER2-Positive Tumors

Contact Info

Product

Resources

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Macrophage Membrane‐Modified MoS₂ Quantum Dots as a Nanodrug for Combined Multi‐Targeting of Alzheimer's Disease