Nicotine patches used in combination with e-cigarettes (with and without nicotine) for smoking cessation: a pragmatic, randomised trial

Walker, Natalie; Parag, Varsha; Verbiest, Marjolein; Laking, George; Laugesen, Murray; Bullen, Chris

doi:10.1016/s2213-2600(19)30269-3

Cited by 142 publications

(150 citation statements)

References 27 publications

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“…Together these studies show that nicotine vaping improves cessation over NRT when used alone or with patches . The magnitude of the benefit is that between seven and eight extra quitters will result per 100 who use vaping to try to quit.…”

Section: Can Vaping Facilitate Cessation?mentioning

confidence: 78%

“…in New Zealand randomised 1124 smokers to nicotine patch‐only ( n = 125), nicotine patch plus nicotine vaping ( n = 500) and nicotine patch plus nicotine‐free vaping ( n = 499). All subjects were offered behavioural support . Those randomised to combined patch and nicotine vaping had triple the biochemically validated continuous abstinence rates of the patch‐only group at 6 months (7% vs. 2%).…”

Section: Can Vaping Facilitate Cessation?mentioning

confidence: 99%

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Could vaping help lower smoking rates in Australia?

Mendelsohn

Hall

Borland

2020

Drug and Alcohol Review

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In this brief article, we review the evidence on whether easier access to vaping could help lower smoking rates in Australia. To make a convincing case for vaping the following conditions need to be met: that vaping assists in smoking cessation; that the prevalence of vaping is high enough to produce measurable effects at a population level; and that the decline in smoking prevalence is slower in countries where vaping is less common. The evidence suggests that these criteria are satisfied. [Mendelsohn C, Hall W, Borland R. Could vaping help lower smoking rates in Australia? Drug Alcohol Rev 2020;39:415-418]

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Section: Can Vaping Facilitate Cessation?mentioning

confidence: 78%

Section: Can Vaping Facilitate Cessation?mentioning

confidence: 99%

Could vaping help lower smoking rates in Australia?

Mendelsohn

Hall

Borland

2020

Drug and Alcohol Review

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“… and Walker et al . randomised controlled trials involved trialists who also received professional behavioural cessation support, which typically improves outcomes, while in real world use insignificant proportions of smokers receive such support. This means the cessation rates of these trials should be discounted in any extrapolation to population‐wide projections.…”

Section: Summary Of E‐cigarette (Ec) Transitions From Wave 1 To Wave mentioning

confidence: 99%

“…In the recent New Zealand randomised controlled trial , after 6 months use, 93% of the patches plus nicotine e‐cigarettes group still smoked (c.f. 98% of the nicotine patches group).…”

Section: Summary Of E‐cigarette (Ec) Transitions From Wave 1 To Wave mentioning

confidence: 99%

Response to Mendelsohn, Borland and Hall's ‘Could vaping help lower smoking rates in Australia?’

Chapman

Daube

2020

Drug and Alcohol Review

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“…They misrepresent the findings of the Walker study by inappropriately converting the conservative continuous abstinence rates into percentages smoking when a significant proportion were of unconfirmed smoking status . The intervention group using nicotine e‐cigarette and nicotine patch includes 54 (10.8%) who reported quitting but did not return a sample for biochemical verification (or in a small number of cases failed it) and 170 who did not complete the 6 month survey (34%).…”

mentioning

confidence: 99%