2010
DOI: 10.4103/0972-124x.65442
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Nicotine and periodontal tissues

Abstract: Tobacco use has been recognized to be a significant risk factor for the development and progression of periodontal disease. Its use is associated with increased pocket depths, loss of periodontal attachment, alveolar bone and a higher rate of tooth loss. Nicotine, a major component and most pharmacologically active agent in tobacco is likely to be a significant contributing factor for the exacerbation of periodontal diseases. Available literature suggests that nicotine affects gingival blood flow, cytokine pro… Show more

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Cited by 66 publications
(68 citation statements)
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“…In the study of Garg N. et al, 2006, in smokers, the analysed parameters such as LP, superoxide dismutase, catalase, glutathione and total thiol showed increased OS proportionally related to the number of cigarettes smoked per day (21). Nicotine affects gingival blood flow, cytokine production, neutrophil and other immune cell function, as well as connective tissue turnover, all of which can be responsible for overall effects on periodontal tissues (22,23). Furthermore, involvement of salivary differed histamine and increased salivary calcium in smokers exacerbates PD (24,25).…”
Section: Discussionmentioning
confidence: 97%
“…In the study of Garg N. et al, 2006, in smokers, the analysed parameters such as LP, superoxide dismutase, catalase, glutathione and total thiol showed increased OS proportionally related to the number of cigarettes smoked per day (21). Nicotine affects gingival blood flow, cytokine production, neutrophil and other immune cell function, as well as connective tissue turnover, all of which can be responsible for overall effects on periodontal tissues (22,23). Furthermore, involvement of salivary differed histamine and increased salivary calcium in smokers exacerbates PD (24,25).…”
Section: Discussionmentioning
confidence: 97%
“…It can also cause delay in oral wound healing, can contribute significantly for the halitosis, can cause staining of teeth, can trigger negative immune response, can alter the pH of the oral cavity 22,23 .The current article explored the association of usage of tobacco products and the periodontal health parameters in the mining employees and the general population.…”
Section: Discussionmentioning
confidence: 99%
“…As alterações causadas pelo fumo na microbiota e no sistema imunológico são as mais estudadas para elucidar o mecanismo de ação do fumo no periodonto, e estes estudos estão presentes em muitas revisões de literatura Chestnutt, 2000;Johnson;Guthmiller, 2007;Malhotra et al, 2010;Ojima;Hanioka, 2010).…”
Section: Efeitos Biológicos Do Fumo Sobre O Periodontounclassified