Nickel(ii) and copper(ii) complexes with pyridine-containing macrocycles bearing an aminopropyl pendant arm: synthesis, characterization, and modifications of the pendant amino groupElectronic supplementary information (ESI) available: colour versions of Figs. 4, 5 and 7. See http://www.rsc.org/suppdata/dt/b2/b211489e/

Herrera, Aida M.; Staples, Richard J.; Kryatov, Sergey V.; Nazarenko, Alexander Y.; Rybak‐Akimova, Elena V.

doi:10.1039/b211489e

Cited by 67 publications

(53 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…3 E(F) transition. The k max value is consistent with a pentacoordinate environment around the Ni(II) ion (Herrera et al 2003). In addition, complex 1 and 2 displayed two strong bands in the UV region one at 245 nm attributed to intraligand charge transfer transitions and another at 268 nm assigned to ligand to metal charge transfer transition.…”

Section: Absorption Spectral Studiessupporting

confidence: 54%

Template synthesis of novel carboxamide dinuclear copper (II) complex: spectral characterization and reactivity towards calf-thymus DNA

Mathur

Tabassum

2007

Biometals

View full text Add to dashboard Cite

Dinuclear complexes Bis [aqua 1,8-(1,2-dicarboxamido benzene) 3,6-diazaoctane copper (II)/nickel (II)] tetrachloride (1 and 2) were synthesized by a two component one-pot metal template condensation between phthalic anhydride and 1,8-diamino 3,6-diazaoctane. Elemental analysis, molar conductance measurements, electronic absorption, infra-red, electron paramagnetic resonance, nuclear magnetic resonance, atomic absorption, and electron spray mass spectral studies have been performed to probe the nature and structure of the complexes. The interaction of copper (II) complex with calf thymus (CT-DNA) has been studied by using absorption, emission and circular dichoric spectral methods, viscometry, and cyclic voltammetry. A strong hyperchromism along with a red shift in UV bands and hypochromism in the ligand field band of the complex 1 on interaction with CT-DNA imply a covalent mode of DNA binding. This is further confirmed by studying the reactivity of complex 1 using circular dichroism and viscosity measurements. The variation in relative emission intensity of DNA-bound ethidium bromide observed upon treatment with the complex 1 parallel the trend of DNA binding studies. Cyclic voltammetry studies reveal that the complex 1 prefers to bind to DNA in Cu(II) rather than Cu(I) oxidation state.

show abstract

Section: Absorption Spectral Studiessupporting

confidence: 54%

Template synthesis of novel carboxamide dinuclear copper (II) complex: spectral characterization and reactivity towards calf-thymus DNA

Mathur

Tabassum

2007

Biometals

View full text Add to dashboard Cite

show abstract

“…According to Hathaway and Billing [23], in our homo-binuclear Cu(II) complex, the G value comes out to be 6.33 which acclaims, the spin exchange interaction between the two copper ions were negligible . Thus, the values of EPR were in agreement with those obtained from the electronic spectra also support octahedral geometry for Cu(II) complex [24].…”

Section: Fig 2b:-mass Spectrum Of Homo-binuclear Cu(ii) Complex Thersupporting

confidence: 85%

SYNTHESIS, SPECTROSCOPIC, ANTICANCER, ANTIMICROBIAL AND ANTIOXIDANT STUDIES OF HOMO-BINUCLEAR Cu(II), Co(II), Ni(II) AND Mn(II) COMPLEXES WITH POLYDENTATE SCHIFF BASE LIGAND.

Rajendran¹,

Govindharaji²,

Chozhanathmisra³

et al. 2017

IJAR

View full text Add to dashboard Cite

A series of homo-binuclear Cu(II), Co(II), Ni(II) and Mn(II) metal complexes of Schiff base which was derived from 2,6-diaminopyridine and glyoxal have been synthesized. The plausible geometry of Schiff base and its binucleating metal complexes were examined by means of elemental and thermal analysis, molar conductance, 1 HNMR, UV-Vis, IR, ESR and mass spectra. From the spectral studies, a six coordinate environment around the metal dimers was confirmed. Both of the Schiff base and its metal complexes were tested for their in vitro antimicrobial activities against some bacterial and fungal strains. Schiff base and its metal complexes were also investigated for its cytotoxic effect against human breast cancer (MCF7) cell lines and it was observed that homo-binuclear Cu(II) and Co(II) complexes showed a good antitumor activity. The antioxidant activity was measured by DPPH method and the result showed that few metal complexes have been more potential activity. [7]. Recently, abundant research on macrocyclic complexes have been focused on species containing the first-row transition metal Schiff base [8]. Furthermore, pyridine based Schiff bases were a significant class of bioactive compounds in medicinal and pharmaceutical fields [9,10]. The above results encouraged making the present study that deals with the synthesis and characterization of heterocyclic homo-binuclear Schiff base complexes derived from 2,6-diaminopyridine and glyoxal containing a NO donor system with some divalent metal ions, namely Cu(II), Co(II), Ni(II) and Mn(II) along with their better biological activity due to their potentially useful properties.

show abstract

“…The trend g k > g ? > 2 reveals that the unpaired electron is present in the d x 2 Ày 2 orbital [46]. For a Cu II complex, g k is a parameter sensitive enough to indicate covalence.…”

Section: Results Andmentioning

confidence: 99%

Synthesis and Biophysical Studies of Bis‐Macrocyclic Cobalt/Copper(II) Complexes Having a Pyridine Spacer with CT DNA and 5′‐GMP

Arjmand

Aziz

2009

Chemistry & Biodiversity

View full text Add to dashboard Cite

New bis-macrocyclic complexes of Co(III), 1, Ni(II), 2, and Cu(II), 3, containing pyridyl bridges between 13-membered macrocyclic subunits, have been synthesized via an in situ one-pot template condensation reaction (IOPTCR). The proposed structures of these new dinuclear complexes are consistent with the data obtained from elemental analysis, molar conductance, IR, EPR, UV/VIS, (1)H- and 13C-NMR, and ESI-MS. The complexes 2 and 3 possess square-planar geometry with four secondary N-atoms coordinated to the metal ion, while complex 1 reveals octahedral geometry in solution due to coordinated H(2)O molecules. DNA-Binding properties of the complexes 1 and 3 were investigated by absorption and emission titrations, cyclic voltammetry, and viscosity measurements. Complexes 1 and 3 are strong DNA binders with binding constants, K(b), of 1.64 x 10(5) and 2.05 x 10(5) M(-1), respectively. Hyperchromism, decrease in emission intensity of DNA-bound ethidium bromide (EB), and changes observed in the viscosity and cyclic voltammograms in the presence of added metal complexes reveals that the complexes bind to DNA predominantly by electrostatic attraction, substantiated by absorption titration with 5'-GMP.

show abstract

Cited by 67 publications

References 51 publications

Template synthesis of novel carboxamide dinuclear copper (II) complex: spectral characterization and reactivity towards calf-thymus DNA

Template synthesis of novel carboxamide dinuclear copper (II) complex: spectral characterization and reactivity towards calf-thymus DNA

SYNTHESIS, SPECTROSCOPIC, ANTICANCER, ANTIMICROBIAL AND ANTIOXIDANT STUDIES OF HOMO-BINUCLEAR Cu(II), Co(II), Ni(II) AND Mn(II) COMPLEXES WITH POLYDENTATE SCHIFF BASE LIGAND.

Synthesis and Biophysical Studies of Bis‐Macrocyclic Cobalt/Copper(II) Complexes Having a Pyridine Spacer with CT DNA and 5′‐GMP

Contact Info

Product

Resources

About