2021
DOI: 10.3892/etm.2021.10057
|View full text |Cite
|
Sign up to set email alerts
|

NICE‑3‑knockdown induces cell cycle arrest and autophagy in lung adenocarcinoma cells via the AKT/mTORC1 signaling pathway

Abstract: The NICE-3 protein serves an oncogenic role in hepatocellular carcinoma, but its role in lung adenocarcinoma (LUAD) remains unknown. The aim of the present study was to investigate the potential role and underlying mechanisms of NICE-3 in LUAD. In the present study, NICE-3 expression in LUAD tissues and its association with patient prognosis were analyzed using datasets from The Cancer Genome Atlas and Gene Express Omnibus. After NICE-3-knockdown with small interfering RNA in LUAD cells, cell proliferation was… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

2022
2022
2022
2022

Publication Types

Select...
1

Relationship

1
0

Authors

Journals

citations
Cited by 1 publication
(1 citation statement)
references
References 22 publications
0
1
0
Order By: Relevance
“…Western blot analysis was conducted as described previously ( Du et al, 2021 ). Briefly, the cells were washed three times with ice cold PBS, and lysed with RIPA buffer containing 1% protease and 1% phosphatase inhibitor (Boston Bioproducts, Milford, MA, USA).…”
Section: Methodsmentioning
confidence: 99%
“…Western blot analysis was conducted as described previously ( Du et al, 2021 ). Briefly, the cells were washed three times with ice cold PBS, and lysed with RIPA buffer containing 1% protease and 1% phosphatase inhibitor (Boston Bioproducts, Milford, MA, USA).…”
Section: Methodsmentioning
confidence: 99%