Next-Generation Hardware Advances in CT: Cardiac Applications

Kwan, Alan C.; Pourmorteza, Amir; Stutman, D.; Bluemke, David A.; Lima, João A.C.

doi:10.1148/radiol.2020192791

Cited by 38 publications

(26 citation statements)

References 99 publications

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“…Compared with previous energy-integrating detector CT systems, this first-generation dual-source full fieldof-view PCD CT can detect and weigh single photons on the basis of their energies, enabling spectral separation and multi-material decomposition (1)(2)(3). Prototype PCD CT systems have been shown to provide improved spatial resolution, dose efficiency, contrast-to-noise ratio (CNR), and lower image noise (4)(5)(6)(7)(8)(9)(10)(11)(12).…”

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confidence: 99%

Quantum Iterative Reconstruction for Abdominal Photon-counting Detector CT Improves Image Quality

et al. 2022

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Background: An iterative reconstruction (IR) algorithm was introduced for clinical photon-counting detector (PCD) CT.Purpose: To investigate the image quality and the optimal strength level of a quantum IR algorithm (QIR; Siemens Healthcare) for virtual monoenergetic images and polychromatic images (T3D) in a phantom and in patients undergoing portal venous abdominal PCD CT. Materials and Methods:In this retrospective study, noise power spectrum (NPS) was measured in a water-filled phantom. Consecutive oncologic patients who underwent portal venous abdominal PCD CT between March and April 2021 were included. Virtual monoenergetic images at 60 keV and T3D were reconstructed without QIR (QIR-off; reference standard) and with QIR at four levels (QIR 1-4; index tests). Global noise index, contrast-to-noise ratio (CNR), and voxel-wise CT attenuation differences were measured. Noise and texture, artifacts, diagnostic confidence, and overall quality were assessed qualitatively. Conspicuity of hypodense liver lesions was rated by four readers. Parametric (analyses of variance, paired t tests) and nonparametric tests (Friedman, post hoc Wilcoxon signed-rank tests) were used to compare quantitative and qualitative image quality among reconstructions. Results:In the phantom, NPS showed unchanged noise texture across reconstructions with maximum spatial frequency differences of 0.01 per millimeter. Fifty patients (mean age, 59 years 6 16 [standard deviation]; 31 women) were included. Global noise index was reduced from QIR-off to QIR-4 by 45% for 60 keV and by 44% for T3D (both, P , .001). CNR of the liver improved from QIR-off to QIR-4 by 74% for 60 keV and by 69% for T3D (both, P , .001). No evidence of difference was found in mean attenuation of fat and liver (P = .79-.84) and on a voxel-wise basis among reconstructions. Qualitatively, QIR-4 outperformed all reconstructions in every category for 60 keV and T3D (P value range, ,.001 to .01). All four readers rated QIR-4 superior to other strengths for lesion conspicuity (P value range, ,.001 to .04). Conclusion:In portal venous abdominal photon-counting detector CT, an iterative reconstruction algorithm (QIR; Siemens Healthcare) at high strength levels improved image quality by reducing noise and improving contrast-to-noise ratio and lesion conspicuity without compromising image texture or CT attenuation values.

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confidence: 99%

Quantum Iterative Reconstruction for Abdominal Photon-counting Detector CT Improves Image Quality

et al. 2022

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“…14 Important technological challenges for PCCT include detector related artifacts such as cross-talk and pulse pile up effects. 3,7 The associated high costs of producing PCCT detectors may limit routine clinical use on a wide scale in the near term as well. 7 The potential of PCCT for cardiac applications in particular has been recently reviewed by Sandfort et al 8 , while more data on systems, either in research or clinical use, are expected to emerge soon.…”

Section: Current Methods and Challenges To Achieve Ultra-high Spatial...mentioning

confidence: 99%

“…At present, new system designs are being introduced to tackle the next challenge of providing much greater spatial resolution from the 0.400 -0.500 mm to the 0.150 -0.200 mm range. 3 One area of particular interest is cardiovascular imaging, an application for which improved spatial resolution could be particularly beneficial. Whereas for visualization of major epicardial coronary arteries CT angiography has become an established alternative to invasive coronary angiography (ICA), imaging artifacts due to partial volume effects hinder accurate evaluation of smaller and calcified epicardial arterial segments with current systems.…”

Section: Introductionmentioning

confidence: 99%

CT imaging with ultra-high-resolution: Opportunities for cardiovascular imaging in clinical practice

Schuijf¹,

Lima²,

Boedeker³

et al. 2022

Journal of Cardiovascular Computed Tomography

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“…The images showed densely calcified plaques and various narrow areas, which were difficult to identify with conventional CT examination ( 104 ). However, this technology has not been applied in humans, only in vitro or animal research ( 105 ).…”

Section: Current Available Non-clinical New Ct Techniquesmentioning

confidence: 99%

Advances in CT Techniques in Vascular Calcification

Zhang

Feng

et al. 2021

Front. Cardiovasc. Med.

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Vascular calcification, a common pathological phenomenon in atherosclerosis, diabetes, hypertension, and other diseases, increases the incidence and mortality of cardiovascular diseases. Therefore, the prevention and detection of vascular calcification play an important role. At present, various techniques have been applied to the analysis of vascular calcification, but clinical examination mainly depends on non-invasive and invasive imaging methods to detect and quantify. Computed tomography (CT), as a commonly used clinical examination method, can analyze vascular calcification. In recent years, with the development of technology, in addition to traditional CT, some emerging types of CT, such as dual-energy CT and micro CT, have emerged for vascular imaging and providing anatomical information for calcification. This review focuses on the latest application of various CT techniques in vascular calcification.

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Next-Generation Hardware Advances in CT: Cardiac Applications

Cited by 38 publications

References 99 publications

Quantum Iterative Reconstruction for Abdominal Photon-counting Detector CT Improves Image Quality

Quantum Iterative Reconstruction for Abdominal Photon-counting Detector CT Improves Image Quality

CT imaging with ultra-high-resolution: Opportunities for cardiovascular imaging in clinical practice

Advances in CT Techniques in Vascular Calcification

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