Next-Generation Continuous Metabolite Sensing toward Emerging Sensor Needs

Abstract

This article discusses the emergent biosensor technology focused on continuous biosensing of metabolites by non-invasive sampling of body fluids emphasized on physiological monitoring in mobility-constrained populations, resource-challenged settings, and harsh environments. The boom of innovative ideas and endless opportunities in healthcare technologies has transformed traditional medicine into a sustainable link between medical practitioners and patients to provide solutions for faster disease diagnosis. The future of healthcare is focused on empowering users to manage their own health. The confluence of big data and predictive analysis and the internet of things (IoT) technology have shown the potential of converting the abundant health profile data amassed from medical diagnosis of patients into useable information, whilst allowing caregivers to provide suitable treatment plans. The implementation of the IoT technology has opened up advanced approaches in real-time, continuous, remote monitoring of patients. Wearable, point-of-care biosensors are the future roadmap to providing direct, real-time information of health status to the user and medical professionals in this digitized era.

Digital Phenotyping in Livestock Farming

“…Sweat is a form of moisture loss that is directly associated with heat tolerance. The composition of sweat also explains physiological processes happening within an animal through the compounds it contains, such as lactate, an indicator of physical stress [19,36].…”

“…Accessibility also includes affordability, a factor that will hopefully increase with the development of tailored systems. Some studies have found accurate values from sensors that only take hourly readings, as opposed to continuous readings [36]. This method could increase affordability by saving battery power and data storage space.…”

Digital Phenotyping in Livestock Farming

“…Sweat is a form of moisture loss that is directly associated with heat tolerance. The composition of sweat also explains physiological processes happening within an animal through the compounds it contains, such as lactate, an indicator of physical stress [16,32].…”

“…Accessibility also includes affordability, a factor that will hopefully increase with the development of tailored systems. Some studies have found accurate values from sensors that only take hourly readings, as opposed to continuous readings [32]. This method could increase affordability by saving battery power and data storage space.…”

State of Sweat: Emerging Wearable Systems for Real-Time, Noninvasive Sweat Sensing and Analytics

“…This perspective offers an overview of the current state-of-the-art for wearable sweat biosensors, with particular emphasis on the application use cases for these sensors. The nascent field is of considerable interest with recent reviews ,,,− contextualizing the progress of wearable sweat sensors within the scope of skin-interfaced devices, ,,,,, sensing technologies, ,,,− specific applications, ,,,,,,, material systems, , and fabrication methods . By contrast, this perspective highlights the most advanced translational embodiments spanning the fundamental use cases for these platforms in relationship to sensing targets.…”