Newly diagnosed multiple sclerosis in state of Qatar

Akhtar, Naveed; Elsetouhy, Ahmed; Deleu, Dirk; Kamran, Saadat; Al-Hail, Hassan; Elalamy, Osama; Mesraoua, Boulenouar; Sokrab, Tag-Eldin O.; Kamil, Hajjul; Melikyan, Gayane; D’Souza, Atlantic; Osman, Yasir; Imam, Yahia

doi:10.1016/j.clineuro.2012.12.035

Cited by 14 publications

(14 citation statements)

References 30 publications

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“…However, up to now, MS origin, prevalence, and geographical allocation are not blatant. The reported period of prevalence in Isfahan/Iran showed a remarkable rise in the prevalence of MS (8)(9)(10)(11)(12)(13)(14)(15)(16). Studies in Arab countries have also demonstrated that MS prevalence is on the rise.…”

Section: Contextmentioning

confidence: 99%

“…Studies in Arab countries have also demonstrated that MS prevalence is on the rise. The pattern of disease in Qatar seems to be different from other Middle East countries from its milder clinical and aggressive radiologic disease presentations (2,12). Therefore, a review related to a comparison of the epidemiology of MS in Iran and other countries in the Middle East is of interest and was investigated.…”

Section: Contextmentioning

confidence: 99%

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A Review of Geoepidemiological Differences of Multiple Sclerosis in Iran and Other Middle East Countries

Tolou-Ghamari

2014

Arch Neurosci

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Context: Review of epidemiological studies of different geographical regions show a wide variation in the prevalence of multiple sclerosis (MS) worldwide. This study compares related geoepidemiological differences in prevalence of MS in the Middle East. Evidence Acquisition: Key words relevant to "prevalence of multiple sclerosis" were searched for with countries in the Middle East. Results: A prevalence of 31-55 per 100,000 individuals has been reported for Persian Gulf countries. The reported prevalence per Kuwait (n = 85.05) and United Arab Emirate (n = 54.4) seems to be high. The reported prevalence for Turkey and Jordan were 51 and 20, correspondingly. Within Iran, the highest and lowest prevalence seem to belong to Isfahan (n = 93.06) and Golestan (n = 18.0), respectively. Immunomodulating drugs such as Interferon-beta as a first-line therapy; and cyclophosphamide, methotrexate, mitoxantrone, and azathioprine have been considered as second-line therapies. Conclusions:The high prevalence of MS in the Middle East might be pointed toward the adverse effects of low vitamin D, individual daily life, smoking, Epstein-Barr virus infection, hereditary affects, and a history of depression.

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Section: Contextmentioning

confidence: 99%

Section: Contextmentioning

confidence: 99%

A Review of Geoepidemiological Differences of Multiple Sclerosis in Iran and Other Middle East Countries

Tolou-Ghamari

2014

Arch Neurosci

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“…Some studies in the Arabian Gulf regions indicate clinically heterogeneous diagnoses of MS [ 12 ]. Akhtar et al [ 13 ] have examined correlations of MS among newly diagnosed individuals in Qatar. The study indicates that MS in that particular population is marked by milder clinical symptoms that tend to be of the ‘relapsing remitting’ type, though with “aggressive radiologic disease presentation”.…”

Section: Introductionmentioning

confidence: 99%

Magnitude and concurrence of anxiety and depression among attendees with multiple sclerosis at a tertiary care Hospital in Oman

et al. 2015

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BackgroundAnxiety, depression and functional impairments are commonly reported by persons with multiple sclerosis (PwMS) but no data, to our knowledge, has emerged from an Arab Islamic population. The study aims to investigate the prevalence of anxiety, depression and related disabilities among PwMS attending tertiary care in Sultan Qaboos University Hospital (SQUH), one of the urban hospitals in Oman.MethodsConsecutive and consenting PwMS (n = 57) and healthy subjects (n = 53) completed the following measures: Hospital Anxiety and Depression Scale (HADS) which was used to measure anxiety (cut-point >7) and depression (>7); and Expanded Disability Status Scale (EDSS) to measure the level of disability (≥5). Characteristics such as socio-demographic and clinical variables were also explored.ResultsFifty seven subjects with multiple sclerosis (MS) met the inclusion criteria. The majority of them were females who were 40 years old or younger and the majority were employed and unmarried. Approximately 86 % of the participants were using beta interferon, 96 % scored ≥5 in EDSS. MS of the Relapsing-Remitting type constituted the majority of the cohort (94 %). Approximately 35 % and 51 % endorsed symptoms of anxiety and depression respectively. The MS group scored significantly higher than controls on HADS measurements of depression and anxiety.ConclusionDisability and symptoms of anxiety and depression are common among the PwMS attendees of tertiary care hospital in Oman. Such psychosocial variables have been largely unreported emerging from non-western populations. As these variables are strong indicators of the burden of MS, resolute effort is needed to address such psychosocial dysfunctions in the algorithms of care for PwMS in the Arab Islamic part of the world.

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“…Traditionally, the current dilemma regarding early justification of the clinical and pathological manifestation of Hirnsklerose, also known as brain sclerosis or multiple sclerosis (MS), began in 1849 with Friedrich von Frerichs (1). MS is a recurrent neurological disease with growing incidence and prevalence worldwide and in the Middle East (2)(3)(4)(5).…”

Section: Introductionmentioning

confidence: 99%

Preliminary Study of Differences Between Prevalence of Multiple Sclerosis in Isfahan and its’ Rural Provinces

Tolou-Ghamari

2015

Arch Neurosci

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Background: Previous publications categorized Isfahan as a high-risk area with regard to the prevalence and incidence of multiple sclerosis (MS). Objectives: Till to date, there have been no studies differentiating between the prevalence of MS in Isfahan and its rural provinces. Patients and Methods: A retrospective study of 4,209 patients with MS was conducted and recorded by the deputy of health at the Isfahan university of medical sciences in 2013. Demographic variables and place of birth were recorded in Excel. Descriptive and comparative analyses were conducted using SPSS. Results: For Isfahan and its rural provinces, the calculated prevalence of MS could be referred as P = 84.14. The calculated prevalence of MS for Isfahan was as P = 27.61. It seems that the highest MS populations are located in the Isfahan rural southwest provinces. The place of birth in 52% was Isfahan. The number of women (78%) was higher than that of men (22%), and 90% of the population was young (range: 20-50 years old). Conclusions: The outcome of this preliminary study suggested that Isfahan and its rural provinces might be categorized as two distinct regions for epidemiology of MS. Medium-risk areas included Isfahan, and high-risk areas included the Isfahan rural southwest provinces. Further advanced studies in this direction are recommended.

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Newly diagnosed multiple sclerosis in state of Qatar

Cited by 14 publications

References 30 publications

A Review of Geoepidemiological Differences of Multiple Sclerosis in Iran and Other Middle East Countries

A Review of Geoepidemiological Differences of Multiple Sclerosis in Iran and Other Middle East Countries

Magnitude and concurrence of anxiety and depression among attendees with multiple sclerosis at a tertiary care Hospital in Oman

Preliminary Study of Differences Between Prevalence of Multiple Sclerosis in Isfahan and its’ Rural Provinces

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