2023
DOI: 10.1016/j.apsb.2022.12.021
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Newly developed gas-assisted sonodynamic therapy in cancer treatment

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Cited by 15 publications
(6 citation statements)
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“…The degradability of MOFs under physiological conditions can be a primary determinant of their toxicity and efficacy in vivo. , To explore this issue, TEM images of LPCN-224 nanoparticles dispersed in 0.9% saline, DMEM supplemented with 10% FBS, and PBS (pH 7.4) for different periods were captured, and the relevant results are shown in Figure h. After being dispersed in 0.9% saline and DMEM (+10% FBS) for 24 h, the nanoparticles basically showed a spherical morphology.…”
Section: Resultsmentioning
confidence: 99%
“…The degradability of MOFs under physiological conditions can be a primary determinant of their toxicity and efficacy in vivo. , To explore this issue, TEM images of LPCN-224 nanoparticles dispersed in 0.9% saline, DMEM supplemented with 10% FBS, and PBS (pH 7.4) for different periods were captured, and the relevant results are shown in Figure h. After being dispersed in 0.9% saline and DMEM (+10% FBS) for 24 h, the nanoparticles basically showed a spherical morphology.…”
Section: Resultsmentioning
confidence: 99%
“…As a safe and effective treatment modality, gas therapy has attracted extensive concern as a way to enhance the efficacy of SDT [ 168 ]. These gases with special therapeutic effects include H 2 S, CO 2 , O 2 , NO, CO, etc ., each of which has a different antitumor mechanism.…”
Section: Isdt For Cancermentioning
confidence: 99%
“…This phenomenon encompasses the formation, growth, and bursting of microbubbles (MBs), along with persistent oscillation. In addition to cavitation, mechanisms such as thermal decomposition and sonoluminescence play a role in activating sonosensitizers for ROS production [82]. Drawing inspiration from PDT, SDT's significant benefit is its deep tissue-and organ-penetration capabilities without the need for radiation, offering lower tissue attenuation and deep tumor-tissue penetration contingent on the ultrasound frequency used.…”
Section: Sonodynamic Therapymentioning
confidence: 99%