Newer Nonfluoride Remineralizing Agents: An Insight

Abstract

Modern-day dentistry has shifted its focus from Black's "extension for prevention" to prevention of extension, however, the current ideology of dentistry stresses on management of noncavitated carious lesions noninvasively through remineralization in an attempt to prevent disease progression, and to improve strength, esthetics, and function of teeth. The oral cavity is an arena involving constant fight between remineralizing and demineralizing factors. This relationship determines the integrity and strength of the tooth structure. The lopsidedness leads to rapid demineralization and decomposition of the tooth structure. In recent past an irrefragable explosion of fervor in technologies for remineralization of enamel and dentin or desensitization of exposed dentin affected by dental erosion has taken place. Remineralization is an innate repair process of reinstating ions back in the hydroxyapatite's lattice structure. The fundamental aspect is the use of remineralizing agents to tooth structure to control the demineralization/ remineralization activity. The present review draws attention to the current components available for remineralization therapy and its application in clinical practice.

Assessment of Efficiency of Bioactive Glass, Self-Assembling Peptide, and Ozone Remineralising Agents on Artificial Carious Lesion

“…Ozone is capable of altering acidogenic and aciduric microorganisms to normal commensalism. The mechanism of Heal Ozone's action is related to ozone's potent antimicrobial properties and its ability to oxidize proteins associated with caries [15].…”

Effect of different surface treatments on the microhardness and colour change of artificial enamel lesions

“…Therefore, increasing the bioavailability of calcium and phosphate ions for remineralization. 10 However, due to the harsh situation of the oral cavity, these agents are subjected to dilution and washing out by saliva. 7 Also, they require time and patient compliance.…”

“…CPP‐ACP complex is a well‐known remineralizing agent that aims to reverse the demineralizing process by precipitating on the tooth and by dissolving in the saliva. Therefore, increasing the bioavailability of calcium and phosphate ions for remineralization 10 . However, due to the harsh situation of the oral cavity, these agents are subjected to dilution and washing out by saliva 7 .…”

Comparative evaluation of efficacy of bioactive glass, tricalcium phosphate, and ozone remineralizing agents on artificial carious lesion

“…[ 3 ] The mechanism of healing ozone's action is related to ozone's potent antimicrobial properties and its ability to oxidize proteins associated with caries. [ 4 ]…”