Newborn screening for congenital heart defects: a systematic review and cost-effectiveness analysis

Abstract

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Rapid testing for group B streptococcus during labour: a test accuracy study with evaluation of acceptability and cost-effectiveness

“…Antenatal screening for a variety of conditions has become routine and all women in this study will have been offered tests for conditions in the fetus and, to a lesser extent, themselves during pregnancy. The extensive literature on antenatal screening and neonatal screening suggests that, although it is highly acceptable to most parents, 105 it can have a psychological cost regardless of the test results. 106,107 Raising the subject of screening in itself may affect the psychological well-being of parents and affect their relationship with their baby.…”

Epidemiology and Etiology of Congenital Heart Diseases

“…diagnosis of life-threatening CHD ranges from £4,900 for pulse oximetry to £4.5 million for screening echocardiography (Knowles et al, 2005). Hence, the public health officers need to consider appropriate methods of CHD detections for their countries.…”

Yenidoğanda Satürasyon Taraması

“…Hayatı tehdit edici konjenital kalp hastalıklarını başarı ile tarayabilecek yöntemlerin başarıları, değişik çalışmalarda tartışılmıştır 2,3,4,11,13,22 .Yenidoğan döneminde metabolik, endokrinolojik taramalar kütle spektrofotometrisi ve biyokimyasal ölçümlerle yapılmakta iken; kardiyolojik taramalar için fizik muayene, vital bulgular vital ölçümetrik parametrelerin (satürasyon) ve ultrasonografik yöntemlerin kullanımı gündeme gelmiştir. Yapılan çalışmalarda tek başına fizik muayene ile sensitivite %.32, antenatal USG taraması ile % 20-44 olarak bulunmuştur 1,11,23,24 .…”

“…Yapılan çalışmalarda, pulse oksimetre ile yenidoğan taramanın uygun yada en azından nötr maliyetli bir uygulama olduğu tahmin edilmektedir 1,2,8,14 . Üstelik pulse oksimetre ile taramanın, gerek kütle spektrofotometri gerektiren metabolik hastalıkların taranmasından, gerekse işitme taramalarından daha düşük maliyetli olduğu düşünülmektedir 14,37,38 .…”

“…Doğumsal kalp hastalıkları yenidoğan döneminde anomalilere bağlı ölümlerin %40'ından sorumludur 1,2 . Doğumsal kalp hastalıkları yenidoğan dönemi boyunca semptomatik olmayabilir [3][4][5] .…”