New trends in inflammatory bowel disease epidemiology and disease course in Eastern Europe

Lovász, Barbara D.; Golovics, Petra A.; Végh, Zsuzsanna; Lakatos, László

doi:10.1016/j.dld.2012.08.020

Cited by 45 publications

(36 citation statements)

References 60 publications

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“…IBD has traditionally been thought of as a disease of the Western hemisphere, however there is an increasing incidence in Japan, Hong Kong, Korea and Eastern Europe [62,63]. Although still rarer, an increasing incidence of IBD is also being identified in South Africa, South America and Saudi Arabia [64,65,66].…”

Section: Diet In the Etiology Of Ibdmentioning

confidence: 99%

An Examination of Diet for the Maintenance of Remission in Inflammatory Bowel Disease

Haskey

Gibson

2017

Nutrients

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Diet has been speculated to be a factor in the pathogenesis of inflammatory bowel disease and may be an important factor in managing disease symptoms. Patients manipulate their diet in attempt to control symptoms, often leading to the adoption of inappropriately restrictive diets, which places them at risk for nutritional complications. Health professionals struggle to provide evidence-based nutrition guidance to patients due to an overall lack of uniformity or clarity amongst research studies. Well-designed diet studies are urgently needed to create an enhanced understanding of the role diet plays in the management of inflammatory bowel disease. The aim of this review is to summarize the current data available on dietary management of inflammatory bowel disease and to demonstrate that dietary modulation may be an important consideration in managing disease. By addressing the relevance of diet in inflammatory bowel disease, health professionals are able to better support patients and collaborate with dietitians to improve nutrition therapy.

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Section: Diet In the Etiology Of Ibdmentioning

confidence: 99%

An Examination of Diet for the Maintenance of Remission in Inflammatory Bowel Disease

Haskey

Gibson

2017

Nutrients

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“…In the West, the prevalence of IBD is 37 to 249 cases per 100,000 people for UC and from 26 to 319 cases per 100,000 people for CD [6, 7]. By contrast, Eastern Europe, Asia, and other developing countries have a lower IBD incidence [7–9]. The occurrence of UC in Asian countries is higher than that of CD [10].…”

Section: Inflammatory Bowel Disease Prevalence and Increasing Incimentioning

confidence: 99%

“…Dietary Glu can also function as a signal to regulate the gastrointestinal tract via the gut-brain axis [9]. As a precursor of glutathione (GSH), Arg and Pro, Glu is of critical importance in intestinal metabolism and physiology [53].…”

Section: Amino Acids: Application In Inflammatory Bowel Disease Thmentioning

confidence: 99%

Roles of Dietary Amino Acids and Their Metabolites in Pathogenesis of Inflammatory Bowel Disease

Bao

Feng

Yao³

et al. 2017

Mediators of Inflammation

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Inflammatory Bowel Disease (IBD) is a kind of chronic inflammation, which has increasing incidence and prevalence in recent years. IBD mainly divides into Crohn's disease (CD) and ulcerative colitis (UC). It is hard to cure IBD completely, and novel therapies are urgently needed. Amino acids (AAs) and their metabolites are regarded as important nutrients for humans and animals and also play an important role in IBD amelioration. In the present study, the potential protective effects of AAs and their metabolites on IBD had been summarized with the objective to provide insights into IBD moderating using dietary AAs and their metabolites as a potential adjuvant therapy.

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“…Although Romania is known as a lowincidence country of IBD [6], few studies have been conducted so far. According to the latest publications that show a global burden of IBD and increasing incidence in Eastern Europe and considering the lack of studies in Romania, we identified the need for assessing the epidemiology of IBD in the South-East side of Romania.…”

Section: Introductionmentioning

confidence: 99%

Inflammatory Bowel Diseases: focus on epidemiology

Tecchio

Achim

Alexandrescu

et al. 2017

ARS Medica Tomitana

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The worldwide incidence and prevalence of Inflammatory Bowel Diseases (IBD) continues to increase, recent studies showing a future global spread of Inflammatory Bowel Diseases. Epidemiological data coming for Romania are scarce. The aim is to describe epidemiological features of Inflammatory Bowel Diseases in an adult population in the South-East side of Romania. The retrospective and descriptive study included 128 patients: group 1=Crohn’s Disease (CD) (79), group 2=Ulcerative Colitis (UC) (46) and group 3=Unclassified Colitis (Unclassified C) (3). We calculated the prevalence of Inflammatory Bowel Diseases in Constanţa in 2016. The phenotypic distribution was: 62% with Crohn’s Disease, 36% with Ulcerative Colitis and 3 patients with Unclassified Colitis. Crohn’s Disease: The prevalence was 0.11/100000 inhabitants. 51% were female and 49% were male. The age distribution showed a uniform model of the frequency of Crohn’s Disease in patients aged between 21 and 50 years. According to Montreal Classification, ileo-colonic involvement L3 was the most frequent in 47% and 60% patients presented inflammatory phenotype B1. 44% had intestinal complications. 9% had extraintestinal complications. 16.4% required surgical interventions. Ulcerative Colitis: The prevalence was 0.06/100000 inhabitants. We noticed a slight male predominance: 57% were male and 43% female. The age distribution showed a bimodal peak of incidence in patients aged between 21-30 years and 41-50 years. The most common disease extension was left colitis E2 in 47% cases. One patient had an enterovesical fistula. Extraintestinal complications were not reported in this group. No patient required surgical intervention. Unclassified Colitis: 3 male patients with ages between 31-50 years were diagnosed with Unclassified Colitis. Complications or need for surgery were not reported in this group. We noticed the predominance of Crohn’s Disease in our region while in other parts of Romania Ulcerative Colitis is predominant. We suppose that the predominance of Crohn’s Disease in Dobrogea can be due to environmental factors, diet or ethnics, but additional epidemiological studies to define better the association with environmental factors and risk factors for Crohn Disease or Ulcerative Colitis in our region are needed.

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New trends in inflammatory bowel disease epidemiology and disease course in Eastern Europe

Cited by 45 publications

References 60 publications

An Examination of Diet for the Maintenance of Remission in Inflammatory Bowel Disease

An Examination of Diet for the Maintenance of Remission in Inflammatory Bowel Disease

Roles of Dietary Amino Acids and Their Metabolites in Pathogenesis of Inflammatory Bowel Disease

Inflammatory Bowel Diseases: focus on epidemiology

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