New therapeutic approach to corrosive burns of the upper gastrointestinal tract.

Costanzo, J. Di; Noirclerc, M; Jouglard, J; Escoffier, Jeffrey; Cano, Noël; Martin, J; Gauthier, A.

doi:10.1136/gut.21.5.370

Cited by 112 publications

(37 citation statements)

References 8 publications

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“…With the exception of the patients who required emergency surgery, an EGD was routinely performed for acid-ingestion patients to assess injury severity in the upper alimentary tract [6, 7, 8, 9]. Our observations have confirmed the finding of Zargar et al [6]that, compared to the stomach, injury to the esophagus is more prevalent with ingestion of acid agents, while gastric injury is more severe than the esophageal analog.…”

Section: Discussionsupporting

confidence: 81%

Early Surgical Correction for Isolated Gastric Stricture following Acid Corrosion Injury

Tseng

et al. 2002

Dig Surg

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Objective: To evaluate the feasibility and long-term results of early gastric surgery for patients with isolated gastric stricture following acid corrosion injury. Materials and Methods: Upper gastrointestinal (UGI) series was routinely performed around the 4th week after acid corrosion injury. Patients with gastric stricture and no risk of delayed esophageal stricture underwent early solitary gastric surgery, which was defined when performance of the procedure took place within 2 months of the injury. Results: From June 1988 to June 2000, 35 of 378 patients with acid corrosion injury developed isolated gastric stricture. Twenty-four (68.6%) lesions were located in the antrum, and 11 (31.4%) in the gastric body. Postprandial vomiting presented earlier for the antral stricture group (17.6 ± 1.1 versus 25.4 ± 3.4 days after injury; p = 0.005). The UGI series was performed from 16 to 41 days after injury (average 25 days). Of the 35 acid corrosion injury patients in this study, 4 were excluded because of late referrals to our institution or the patient’s hesitation which resulted in delayed surgery. The remaining 31 patients underwent gastric surgery 35.7 ± 3.2 days after ingestion (34.6 ± 3.6 and 38.1 ± 3.4 days for cases of antral and gastric body stricture, respectively). Surgical procedures consisted of hemigastrectomy (n = 16), antrectomy (n = 2), gastroenterostomy (n = 2), subtotal gastrectomy (n = 6), and total gastrectomy (n = 5). There were 4 cases of postoperative complications (12.9%) including adhesion ileus (n = 2), wound infection (n = 1), and massive, postoperative UGI bleeding (n = 1). Surgical mortality was zero. All patients tolerated oral intake well after surgery. During the minimum follow-up period of 1 year, 1 patient developed esophagojejunostomy stenosis, which was resolved by dilation, and there was 1 case of dumping syndrome, which was treated by diet control. Conclusion: Early surgery correction is feasible and safe if patients with isolated gastric stricture following acid corrosion injury are carefully selected. All patients in our study recovered early, with a low morbidity rate.

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Section: Discussionsupporting

confidence: 81%

Early Surgical Correction for Isolated Gastric Stricture following Acid Corrosion Injury

Tseng

et al. 2002

Dig Surg

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“…13 Other authors have not reported any complications with endoscopic procedures. 2 Ingestion of solid alkali usually causes severe burns of the mouth or pharynx or both.…”

Section: Discussionmentioning

confidence: 99%

Corrosive Burns of the Upper Gastrointestinal Tract among Jordanian Children

Hijazeen

1998

Ann Saudi Med

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“…These types of burns may lead to serious clinical pictures that may start with a simple esophagitis and progress towards esophageal perforation. Corrosive esophagitis is a condition encountered in children of age 1-5, whereas it is more commonly seen in adults of age 20-30 3,4 . While corrosive substances are taken in by children in little amounts and often by accident, they are taken in by adults in large amounts for suicidal purposes in general, due to which an esophageal damage progressing more severely in a sequellae fashion occurs 4,5 .…”

Section: Discussionmentioning

confidence: 99%

“…In all the cases, endoscopy was performed up to the region where the initial lesion in esophagus was seen due to the perforation risk caused by further progress. Our endoscopic findings were classified from Grade 0 to Grade 4 according to the findings that varied from a normal and large mucosal edema to deep ulceration and perforation 3 .…”

Section: Endoscopic Evaluationmentioning

confidence: 99%

Clinical features and treatment of corrosive esophagitis

Metin¹,

Aribas²

2016

Cukurova Med J

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AbstractÖz Purpose: The esophageal burns caused by corrosive substances are of great importance since they progress along with serious complications. Here, we have aimed to evaluate our 39 cases we followed up and treated in our clinic due to taking in corrosive substances according to their clinical characteristics and our treatment approaches. Materials and Methods: Thirty nine patients whose file records could be obtained and who were treated for corrosive esophagitis between January 2000 and December 2007 were included in our study. Clinical features and treatment of those cases were recorded and evaluated. Results: The intake rate of corrosive substances was higher in women. The amount of corrosive substance taken in was prominently higher in those having it for suicidal purposes compared to those having it by accident. According to their endoscopic features, 82.1% of the cases were found to have had endoscopic findings referred to as normal or grade 1. While ulcer grade 2-3 comprised 10.3% of all the cases, grade 4 comprised 7.7% of all the cases with severe burns. Conclusion: To stop the oral intake, performing an endoscopic evaluation and making a treatment plan in accordance with the endoscopy results for the patients applying the clinic in the early stage due to the intake of corrosive substances are of great importance in terms of preventing the complications likely to occur. Amaç:Koroziv maddelerin oluşturdukları özofagus yanıkları ciddi komplikasyonlar ile seyrettiği için çok önemlidir. Bu çalışmada kliniğimizde takip ve tedavi ettiğimiz koroziv madde içen 39 olgumuzu klinik özellikleri ve tedavi yaklaşımlarımıza göre değerlendirmeyi amaçladık. Gereç ve Yöntem: Çalışmamıza Ocak 2000-Aralık 2007yılları arasında Selçuk Üniversitesi, Meram Tıp Fakültesi,Göğüs Cerrahi kliniğinde tedavi edilen ve dosya kayıtlarına ulaşılabilen 39 hasta dahil edildi. Bu hastaların klinik özellikleri ve tedavileri kaydedilerek değerlendirildi. Bulgular: Koroziv madde içme oranı kadınlarda daha yüksek idi. İçilen koroziv madde miktarı suisit amaçlı içenlerde yanlışlıkla içenlere oranla belirgin yüksek idi. Endoskopik özelliklerine göre olguların %82.1'inde normal veya evre 1 endoskopi bulgusuna rastlanılmıştır. Evre 2-3 ülser tüm olguların %10.3'ünü oluştururken, evre 4 ağır yanık tüm olguların %7.7'ini oluşturuyordu. Sonuç: Koroziv madde kullanımı sonrası erken dönemde başvuran hastalarda oral alımın kesilmesi, erken evrede endoskopik değerlendirmenin yapılması ve endoskopi sonucuna göre tedavi planının yapılması komplikasyonların önlenmesi açısından büyük öneme sahiptir.

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New therapeutic approach to corrosive burns of the upper gastrointestinal tract.

Cited by 112 publications

References 8 publications

Early Surgical Correction for Isolated Gastric Stricture following Acid Corrosion Injury

Early Surgical Correction for Isolated Gastric Stricture following Acid Corrosion Injury

Corrosive Burns of the Upper Gastrointestinal Tract among Jordanian Children

Clinical features and treatment of corrosive esophagitis

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