New strategy of synthesis, characterization, theoretical study and inhibition effect on mild steel corrosion in acidic solution

Abstract

<p>We report two new different synthesis strategies of an eco-friendly organic dye 3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl diacetate. These methods were based on the reaction of fluorescein with acetic anhydride under different experimental conditions. The synthesized heterocyclic system obtained with excellent yield was characterized by FT-IR, <sup>1</sup>H N.M.R., <sup>13</sup>C N.M.R., and mass spectrometry. This reaction has also been studied theoretically using Gaussian 09 based on the DFT method at B3LYP/6-31G (d, p). The results obtained are in good correlation with those obtained experimentally. The inhibition behavior of the synthetic product has been studied using absorbance difference measurement, the percentage of inhibition efficiency attains 90% at 10<sup>-4</sup>M of NAR3 inhibitor. The surface analysis of mild steel was investigated using scanning electron microscopy (S.E.M.) and Energy Dispersive X-ray (E.D.X.) methods and show the adsorption behavior of inhibitor on the surface of mild steel.</p>

The intelligence way of economical synthesis strategies of an N-alkylcarbazole

“…The carbazole nucleus can be naturally found in the composition of some alkaloids as staurosporine, ellipticine or koenidine, with antibacterial, antifungal, antimalarial properties, antitumoral activity, and potential antidiabetic effect [6,7,8], among them carbazomycins represent an unprecedented class of antibiotics with a carbazole heterocycle [9]. Various researches done on the synthesis of new heterocyclic compounds [10,11,[12][13][14][15][16][17][18], we focused in this work, on the theoretical study of the reaction carried out followed by the effective synthesis of the 9-(prop-2-yn-1-yl)-9H-carbazole with three methods (phase transfer catalysis, microwave, and base + acetone) with the aim to elaborate a new active molecules with an important yield. For us, it is preferable to establish a theoretical study of a synthetic reaction before going to the experimental mode because it will inform us from the start on the path of the reaction and the expected results to save time and minimize losses of energy (use of heating or not) and matter (reaction possible or not).…”