New Rotenoids and Coumaronochromonoids from the Aerial Part of <i>Boerhaavia erecta</i>

Abstract

From the aerial part of Boerhaavia erecta L., three new rotenoids (3, 8, 10) and two new coumaronochromonoids (6, 11) were isolated, together with ten known compounds. The structure of the new compounds was established by one dimensional (1D)-and 2D-NMR spectroscopy, as well as high resolution-electrospray ionization (HR-ESI)-MS analysis. The absolute configuration of compound 11 was determined by UV circular dichroism spectroscopy. Compounds were evaluated for their cytotoxic activity against HeLa (human epithelial carcinoma), NCI-H460 (human lung cancer) and MCF-7 (human breast cancer) cell lines at the concentration of 100 µg/mL. Rotenoids 3, 4 and 5 showed a strong cytotoxic activity against HeLa cell line and rotenoids 5 and 8 showed good activity against MCF-7 cell line.

Chemical Constituents from Apios americana and Their Inhibitory Activity on Tyrosinase

“…Their structures were elucidated by comparing spectroscopic data (CD, ESI-MS, and NMR spectra) with those reported previously. The purified compounds were identified as aromadendrin 5-methyl ether ( 1 ) [ 18 ], lupinalbin A ( 2 ) [ 19 ], genistein ( 3 ) [ 17 ], 2′-hydroxygenistein ( 4 ) [ 17 ], 5-methylgenistein ( 5 ) [ 17 ], barpisoflavone ( 6 ) [ 17 ], 2′-hydroxy-5-methylgenistein-7- O -glucoside ( 7 ) [ 16 ], 2′-hydroxygenistein-7- O -gentibioside ( 8 ) [ 16 ], and genistein-7- O -gentibioside ( 9 ) [ 16 ] ( Figure 1 , Supplementary materials Figures S1–S11 ).…”

Quantitative Analysis of Boeravinones in the Roots of Boerhaavia Diffusa by UPLC/PDA

“…A series of boeravinones, namely boeravinone A–J have been reported from B. diffusa roots (Kadota et al ., ; Lami et al ., , ; Borrelli et al ., ; Ahmed‐Belkacem et al ., ). Recently, boeravinone K–O were reported from aerial parts of B. erecta (Do et al ., ), and we have reported a further four new boeravinones (P–S) from B. diffusa roots (Bairwa et al ., , ).…”

Isolation, Synthesis, and Antisepsis Effects of a C-Methylcoumarinochromone Isolated from Abronia nana Cell Culture

“…Although their structures are similar to those of C -methylrotenoids, the C -methylcoumarinochromones bearing a furan ring instead of a pyran ring have been rarely reported. To the best of our knowledge, boeravinone J, , triquetrumones A, B, and C, and flemingichromone are the only reported C -methylcoumarinochromones so far. A. nana belongs to the plant family Nyctaginaceae, which grows in the desert areas of North America and has not been extensively studied yet.…”