New prenylated isoflavanones and other constituents of Lespedeza bicolor

Two new dihydrofuranoisoflavanones from the leaves of Lespedeza maximowiczi and their inhibitory effect on the formation of advanced glycation end products

“…Plants from the genus Lespedeza have been used as antipyretic, anti-inflammatory, and diuretic agents (Im, 1998). Isoflavanones (Ueno et al, 1973a(Ueno et al, , 1973bMiyase et al, 1999b;Maximov et al, 2004), coumestan (Chen et al, 2008), coumarochromone (Ueno et al, 1973c), phenolic compounds (Miyase et al, 1999a), and chalcone (Miyase et al, 1980) have been isolated from this genus. However, we could not find any previous concerted chemical and biological investigation of the particular species L. maximowiczii.…”

Evaluation of Lespedeza germplasm genetic diversity and its phylogenetic relationship with the genus Kummerowia

“…Flavonoids have been identified in leaves and roots of L. capitata (Wagner et al 1972;Linard et al 1982), L. davidii (Wang et al 1987), and L. formosa (Li et al 1992). Antiallergic and antioxidative compounds (lespedezols, stilbenoids, and prenylated isoflavonones) have been isolated from L. homoloba and L. bicolor stems (Miyase et al 1999a, b;Maximov et al 2004). Overall, Lespedeza plants may contain useful compounds which can contribute to human health.…”

Desmodianone H and uncinanone B, potential tyrosinase inhibitors obtained from Lespedeza maximowiczii by using bioactivity-guided isolation

“…1) About 40 plant species belonging to the genus Lespedeza have been reported; these species show very diverse morphological characteristics. 2) Furthermore, many metabolites, especially isoflavanones, [3][4][5][6] phenolic compounds, 7) , and chalcone 8) have been isolated from species belonging to this genus. Lespedeza plants have traditionally been considered to have antipyretic, anti-inflammatory, and diuretic activities.…”