New Porosimetric Method Based on the 3γ Annihilation Rate. Applications to Materials Science and Medical Imaging

Jasińska, B.; Zgardzińska, B.

doi:10.12693/aphyspola.132.1616

Cited by 3 publications

(3 citation statements)

References 27 publications

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“…Recently, significant differences in PALS parameters between normal and tumor tissues were also observed by the J-PET group in samples of uterine leiomyomatis and normal myometrium tissues taken from women-patients after surgery [21], [22]. In case of all samples from six patients it was found that mean o-Ps lifetime are of about 2 ns, while for normal tissues this value is of about 50 ps lower.…”

Section: Current Pals Application In Biologymentioning

confidence: 89%

Potential for biomedical applications of Positron Annihilation Lifetime Spectroscopy (PALS)

Kubicz

2018

Preprint

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Positron Annihilation Lifetime Spectroscopy (PALS) allows examining structure of materials in nano and sub-nanometer scale. This technique is based on the lifetime and intensity of ortho-positronium atoms in free volumes of given structures. It is mostly used for studies in material sciences, but it can also be used for in vivo imaging of the cell morphology as proposed in [1], [2]. Cancer cells are characterized by an altered macro structure in comparison to normal cells, thus the main objective of these studies is to compare if these differences can be detected on sub-nanometer level and therefore allows to distinguish between normal and cancer cells with application of PALS technique. This perspective will allow for simultaneous determination of early and advanced stages of carcinogenesis, by observing changes in biomechanical parameters between normal and tumour cells, and standard PET examination. Such simultaneous PET imaging and PALS investigations can be performed with the Jagiellonian Positron Emission Tomograph (J-PET) which is a multipurpose detector used for investigations with positronium atoms in life-sciences as well as for development of medical diagnostics.

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Section: Current Pals Application In Biologymentioning

confidence: 89%

Potential for biomedical applications of Positron Annihilation Lifetime Spectroscopy (PALS)

Kubicz

2018

Preprint

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“…0.1883 [38] 0.978 [38] 26.22 [39] 5.18 [39] Ionisation energy (eV) [39] measure crystal defects. Recent studies indicating the full utilisation of positronium formation in medicine are also available [13,14]. Studying electron-matter and positron-matter interactions help us answer questions about the structure of matter and the processes they undergo during the collision.…”

Section: Introductionmentioning

confidence: 99%

Electron and positron backscattering from condensed targets

Sinha¹,

Subraveti²,

Antony³

2021

J. Phys. B: At. Mol. Opt. Phys.

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The backscattering process for electron and positron impinging on condensed targets is studied here. The calculation is performed for Li, Na, Al and Cu atoms in the 500–3000 eV energy range. The well known Vicanek and Urbassek theory is used to determine the backscattering coefficient for present solid atoms. To analyze the elastic scattering cross section, spherical complex optical potential formalism is used. Apart from the backscattering coefficient, momentum transfer cross section, range of penetration, and mean number of wide-angle collisions are also tabulated and compared to the available data. No previous work was found reporting the range of penetration for the atoms. Hence, we also report the electron backscattering coefficient and range of penetration for liquid water for which experimental and theoretical data are available for the range of penetration. The electron backscattering coefficient for liquid water is reported for the first time here.

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“…The innovative construction concept was recently proposed by the J-PET collaboration [24][25][26][27][28][29][30][31]. One of the advantages of J-PET is a possibility of multi-photon imaging [32,33] which enables the diagnosis based on positron and positronium lifetime [16] as well as on the ratio of 3γ and 2γ annihilation rates [17,34,35].…”

Section: Introductionmentioning

confidence: 99%

Human Tissue Investigations Using PALS Technique - Free Radicals Influence

et al. 2017

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The positron annihilation lifetime spectroscopy was applied to the samples of the human uterine leiomyomas and the normal myometrium tissues taken from the selected place of the uterus during a surgery. The method indicated differences in values of the measured positron annihilation lifetime spectroscopy parameters (lifetimes and intensities) between healthy and diseased tissue samples. The additional measurements were performed either in darkness or in presence of visible light which influenced the free radicals present in both kind of tissues and, as a result, made changes in free annihilation and o-Ps decay lifetime and intensity values.

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New Porosimetric Method Based on the 3γ Annihilation Rate. Applications to Materials Science and Medical Imaging

Cited by 3 publications

References 27 publications

Potential for biomedical applications of Positron Annihilation Lifetime Spectroscopy (PALS)

Potential for biomedical applications of Positron Annihilation Lifetime Spectroscopy (PALS)

Electron and positron backscattering from condensed targets

Human Tissue Investigations Using PALS Technique - Free Radicals Influence

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