New Orsellinic Acid Esters from Fungus Chaetomium globosporum

Abstract

Seven new orsellinic acid esters, 1 -7, and four known compounds were isolated from the solid, fermented rice culture of Chaetomium globosporum (cib-132). Their structures were elucidated by 1D-and 2D-NMR spectra, and the relative configuration of compound 1 was determined by X-ray crystallographic analysis.

Metabolic Profiling of Water-Soluble Compounds from the Extracts of Dark Septate Endophytic Fungi (DSE) Isolated from Scots Pine (Pinus sylvestris L.) Seedlings Using UPLC–Orbitrap–MS

“…Furthermore, we were able to find exact masses corresponding to orsellinic acid esters, which have been isolated from the endophytic Chaetomium sp. fungus [16,95,96,97]. However, orsellinic acid ester Globosumone B was not included in the Table 2 because of the chosen intensity limit 1 × 10 7 .…”

Aureonitol Analogues and Orsellinic Acid Esters Isolated from Chaetomium elatum and Their Antineuroinflammatory Activity

“…The substructure from C-1′ to C-8′ could be postulated on the basis of HMBC correlations from H-2′ to C-1′ and C-3′, from H-3′ to C-1′, C-2′, C-4′, and C-5′, from H-5′ to C-3′, C-4′, C-6′, C-7′, and C-8′, from H-7′ to C-5′ and C-6′, and from H-8′ to C-3′ and C-4′. A characteristic IR absorption at 1771.7 cm –1 indicates the presence of a γ-lactone formed between C-1′ and C-4′, which accounts for the degree of unsaturation. The planar structure of 10 was confirmed by the HMBC correlations from H-8′ to C-1.…”