New-onset atrial fibrillation following coronary bypass surgery predicts long-term mortality

Phan, Kevin; Ha, Hakeem; Thomas, Stuart P.; Medi, Caroline; Yan, Tristan D.

doi:10.1016/j.hlc.2014.12.033

Cited by 3 publications

(3 citation statements)

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“…This systematic review and meta-analysis examined the long-term implications of POAF in patients after all types of cardiac operations patients, because previous reviews have only include patients undergoing coronary artery bypass grafting. 2,7 The number of patients and studies included is large, and the results are statistically significant with narrow CIs. Cautious interpretation of unadjusted outcomes is warranted, however, particularly in light of the high degree of heterogeneity between studies.…”

Section: Strengths and Limitationsmentioning

confidence: 99%

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Postoperative Atrial Fibrillation After Cardiac Surgery: A Systematic Review and Meta-Analysis

Eikelboom

Sanjanwala

Lê

et al. 2021

The Annals of Thoracic Surgery

112

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Section: Strengths and Limitationsmentioning

confidence: 99%

“…These results confirm that POAF can no longer be understood as a benign, self-limiting complication of cardiac surgical intervention. 2 It is not clear why patients with new onset POAF after cardiac operations have worse outcomes. One possibility is that POAF occurs in sicker, frailer patients and is therefore a surrogate for increased death.…”

Section: Commentmentioning

confidence: 99%

Postoperative Atrial Fibrillation After Cardiac Surgery: A Systematic Review and Meta-Analysis

Eikelboom

Sanjanwala

Lê

et al. 2021

The Annals of Thoracic Surgery

112

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“…POAF is a frequently encountered complication following cardiac procedures, with incidence rates ranging from 20% to 40% (32,33). In a meta-analysis involving 155,575 patients, POAF incidence occurred in 36,988 patients, with an incidence rate of 23.7% (34).…”

Section: Discussionmentioning

confidence: 99%

Systemic immune–inflammation index for predicting postoperative atrial fibrillation following cardiac surgery: a meta-analysis

Chen,

Liu,

Hsu

et al. 2024

Front. Cardiovasc. Med.

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BackgroundPostoperative atrial fibrillation (POAF) is a frequent complication that may increase morbidity and mortality risk following cardiac surgery. The systemic immune–inflammation index (SII) is an emerging biomarker that provides an integrated measure of inflammation by incorporating neutrophil, lymphocyte, and platelet counts. Recent studies have reported associations between elevated SII and increased POAF risk; however, significant heterogeneity exists regarding its predictive efficacy. This meta-analysis aimed to assess SII's diagnostic efficacy for predicting POAF risk.MethodsTo synthesize existing evidence on the ability of perioperative SII for predicting POAF in patients undergoing cardiac surgery, a systematic review and meta-analysis was conducted. In August 2023, a comprehensive literature search was performed to identify relevant studies reporting SII cutoff values with corresponding sensitivity and specificity. The primary aim was to evaluate SII's diagnostic utility for predicting POAF, whereas secondary outcomes included the pooled incidence of POAF and the relationship between the SII and POAF.ResultsEight studies published between 2021 and 2023 with 3,245 patients were included. Six studies involved coronary artery bypass grafting (CABG) surgery; one encompassed various cardiac procedures, and another focused solely on mitral valve surgery. The pooled incidence of POAF was 23.6% [95% confidence interval (CI), 18.7%–29.2%]. Elevated SII significantly increased the odds of POAF by 3.24-fold (odds ratio, 3.24; 95% CI, 1.6–6.55; p = 0.001). SII's pooled sensitivity and specificity for predicting POAF were 0.80 (95% CI, 0.68–0.89) and 0.53 (95% CI, 0.23–0.8), respectively. The SII had moderate predictive accuracy based on a hierarchical summary receiver operating characteristic (HSROC) area under the curve of 0.78 (95% CI, 0.74–0.81). Subgroup analyses, whether focusing on CABG alone or CABG with cardiopulmonary bypass (CPB), both indicated an area under the HSROC curve of 0.78 (95% CI, 0.74–0.81).ConclusionElevated SII is significantly correlated with an increased POAF risk following cardiac surgery, highlighting its utility as a predictive biomarker. Considering its moderate diagnostic accuracy, further research is essential for clarifying SII's clinical effectiveness, either as an independent predictor or combined with other risk factors, for stratifying patients at high POAF risk.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/, identifier [CRD42023456128].

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Validation of a New Classification Method of Postoperative Complications in Patients Undergoing Coronary Artery Surgery

Kinnunen

Mosorin

Perrotti

et al. 2016

Journal of Cardiothoracic and Vascular Anesthesia

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New-onset atrial fibrillation following coronary bypass surgery predicts long-term mortality

Abstract: women, asymptomatic hypermobile women and women with normal mobility.

Cited by 3 publications

References 0 publications

Postoperative Atrial Fibrillation After Cardiac Surgery: A Systematic Review and Meta-Analysis

Postoperative Atrial Fibrillation After Cardiac Surgery: A Systematic Review and Meta-Analysis

Systemic immune–inflammation index for predicting postoperative atrial fibrillation following cardiac surgery: a meta-analysis

Validation of a New Classification Method of Postoperative Complications in Patients Undergoing Coronary Artery Surgery

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