New-Onset Atrial Fibrillation After Cardiac Surgery: Pathophysiology, Prophylaxis, and Treatment

Lomivorotov, Vladimir V.; Efremov, Sergey; Pokushalov, Evgeny; Karaskov, Alexander

doi:10.1053/j.jvca.2015.08.003

Cited by 59 publications

(94 citation statements)

References 175 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Miyokardiyal atriyal fibrozis AF'ye eşlik eden sık bulgudur. En sık tetikleyen alanlar, sol pulmoner venlere uzanan atriyal miyokard yastıkları, pulmoner venlerin histolojik, anatomik ve elektrofizyolojik özellikleri bu bölgedeki aritmojenik aktiviteye katkıda bulunur [2,3,10] .…”

Section: Patofizyolojiunclassified

“…Yine sempatik ve parasempatik stimülasyon (artmış otomasite, uyarılmış aktivite) AF'a neden olabilir [2,3] .…”

Section: Patofizyolojiunclassified

“…Bunlar iskemi-reperfüzyon, cerrahi manipülasyonlar, inflamasyon ve oksidatif stres üzerine etkili olabilecek n3PUFA (poliansatüre yağ asitleri), kolşisin, nonsteroid antianflamatuarlar, kortikosteroidler, statinler; elektriksel ve yapısal remodeling üzerine etkili olabilecek beta-blokerler, sotalol, magnezyum, amiodaron, kalsiyum kanal blokerleri, botilusmus toksinidir [2,3,12,21] . Bu tedaviler ile POAF üzerine ümit verici bulgular elde edilmesine rağmen, randomize kontrollü çalışmalara gereksinim vardır [22] .…”

Section: Patofizyolojiunclassified

“…KABG sonrası en az 48 saat süreyle EKG monitorizasyonu önerilmektedir (Class 1 öneri, kanıt düzeyi B) (AHA ve ACC). Şüpheli durumda 12 lead EKG çekilmelidir [2,11] .…”

Section: Patofizyolojiunclassified

“…Oluşan yağ infiltrasyonu fibrozise neden olur. Bu durum iyon kanallarında remodeling ve iletim anomalilerine yol açarak atriyal fibrilasyona neden olmaktadır [2,[8][9][10][11] . Yine fibrinolizisin azalması, trombosit aktivasyonu hiper koagülasyona neden olarak stroke oluşumuna neden olmaktadır [11] .…”

Section: Introductionunclassified

See 4 more Smart Citations

Atrial Fibrillation After Cardiac Surgery

Aksun¹,

Eryilmaz²,

Gürbüz³

et al. 2017

GKDA Derg

View full text Add to dashboard Cite

show abstract

Section: Patofizyolojiunclassified

“…Yine sempatik ve parasempatik stimülasyon (artmış otomasite, uyarılmış aktivite) AF'a neden olabilir [2,3] .…”

Section: Patofizyolojiunclassified

“…KABG sonrası en az 48 saat süreyle EKG monitorizasyonu önerilmektedir (Class 1 öneri, kanıt düzeyi B) (AHA ve ACC). Şüpheli durumda 12 lead EKG çekilmelidir [2,11] .…”

Section: Patofizyolojiunclassified

Section: Introductionunclassified

See 3 more Smart Citations

Atrial Fibrillation After Cardiac Surgery

Aksun¹,

Eryilmaz²,

Gürbüz³

et al. 2017

GKDA Derg

View full text Add to dashboard Cite

show abstract

Cardiovascular Management

2020

Manual of Perioperative Care in Adult Cardiac Surgery

View full text Add to dashboard Cite

Controversies in postoperative atrial fibrillation after noncardiothoracic surgery: clinical and research implications

Vallurupalli

Shanbhag

Mehta

2017

Clinical Cardiology

View full text Add to dashboard Cite

Post operative atrial fibrillation after non-cardiothoracic surgery is an increasingly common problem. There is little high quality data to guide clinicians in risk prediction as well as short term and long term management. There appears to be a significant risk of recurrent atrial fibrillation and stroke but effective screening strategies have not been tested. In this commentary, we delineate various controversies in the management of post operative atrial fibrillation and briefly review the available evidence. Prospective studies in this clinically important area of cardiology should be encouraged. K E Y W O R D SAtrial fibrillation, Non-cardiac non-thoracic surgery | INTRODUCTIONAtrial fibrillation (AF) affects >2.5 million Americans and is often diagnosed after both cardiac and noncardiac surgeries. Postoperative atrial fibrillation (POAF) is a common complication after cardiothoracic surgery (CTS), with a reported incidence of 30% to 50% and increases mortality, length of hospital stay, and cost of care. 1 Prevention and management of POAF after cardiac surgery is guided by the results of several randomized controlled trials.On the other hand, POAF after noncardiac and nonthoracic surgery (NCTS) is less well studied. Depending on the type of surgery, the incidence varies widely, but it is approximately 3% among unsel- | POAF OCCURRING AFTER CTS AND NCTSIn this article, we compare and contrast the differences between POAF occurring after CTS and NCTS and discuss controversies in management. | Is the pathophysiology of POAF different after NCTS compared with CTS?After CTS, it is intuitive that direct handling of the heart (which is likely diseased), elevated cardiac pressures, and/or local inflammation can precipitate POAF. 1 As inflammation and local injury subside, POAF often spontaneously resolves. After NCTS, the precipitants of POAF are often more systemic in nature. Some of the known precipitants for POAF after noncardiac surgery are shown in the | Does POAF impact short-term outcomes after NCTS?Evidence suggests that POAF after NCTS is associated with a higher risk of postoperative complications such as bacterial pneumonia and congestive heart failure and leads to increased hospital stay and postoperative mortality. 2,7 In the Perioperative Ischemic Evaluation (POISE) study of perioperative β-blockade use in NCTS, POAF was associated with an increased risk of stroke at 30 days. 8 Based on the factors delineated in table 1, POAF is as much a marker of a sicker

show abstract

New-Onset Atrial Fibrillation After Cardiac Surgery: Pathophysiology, Prophylaxis, and Treatment

Cited by 59 publications

References 175 publications

Atrial Fibrillation After Cardiac Surgery

Atrial Fibrillation After Cardiac Surgery

Cardiovascular Management

Controversies in postoperative atrial fibrillation after noncardiothoracic surgery: clinical and research implications

Contact Info

Product

Resources

About