New method to measure phasic coronary blood velocity in man

Benchimol, Alberto; Stegall, H F; Gartlan, John L.

doi:10.1016/0002-8703(71)90058-5

Cited by 86 publications

(14 citation statements)

References 20 publications

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“…Several methods have been used in the past to provide a quantitatiye means of measuring coronary blood flow in man, including indicator-dilution and radioisotope techniques as well as Doppler ultrasonic flow catheter measurements and densitometric evaluations of coronary angiograms. [1][2][3][4][5][6][7][8] Generally x-ray densitometry is based on the determination of the mean transit time of contrast medium. Mean transit time is defined as the difference between the mean appearance times of the contrast medium measured from the "densograms" (time function of x-ray density) at a proximal site and a distal site over the vessel.…”

mentioning

confidence: 99%

Measurement of systolic and diastolic flow rates in the coronary artery system by x-ray densitometry.

Spiller¹,

Schmiel²,

Pölitz³

et al. 1983

Circulation

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The reliability of a modified videodensitometric and photodensitometric sampling technique for measuring phasic flow rates in the coronary artery system was examined. Electromagnetic flow measurements were performed in a circulatory model with continuous and pulsatile flow and intraoperatively in aortocoronary bypass grafts; cineangiograms were made simultaneously. Based on the front velocities of injected boluses of contrast medium, the densitometric measurement overestimated the electromagnetically measured flow systematically by about 20%. Systolic and diastolic flow rates in aortocoronary bypass grafts and coronary arteries determined from biplane cineangiograms in 34 patients generally revealed the typical pulsatile flow pattern familiar from electromagnetic and ultrasonic flow measurements. Flow velocities in unstenosed coronary arteries were nearly identical before and after branchings of the vessels, whereas the corresponding flow rates were higher in proximal than in distal segments. The identical flow velocities in different branches of the same vessel and the low variability of this parameter in different patients may be a suitable index of the effect of stenoses on coronary arterial blood flow. Circulation 68, No. 2, 337-347, 1983. THE SEVERITY of coronary artery disease is currently estimated by subjective evaluation of morphologic vessel abnormalities visualized by coronary angiography. Several methods have been used in the past to provide a quantitatiye means of measuring coronary blood flow in man, including indicator-dilution and radioisotope techniques as well as Doppler ultrasonic flow catheter measurements and densitometric evaluations of coronary angiograms. 1-8 Generally x-ray densitometry is based on the determination of the mean transit time of contrast medium. Mean transit time is defined as the difference between the mean appearance times of the contrast medium measured from the "densograms" (time function of x-ray density) at a proximal site and a distal site over the vessel.95In an attempt to avoid several methodologic difficulties inherent in this technique, we determined transit times from the fronts of the densograms (appearance From time) instead of the mean appearance time. The flow rates determined from the front velocities were compared with those flow values measured electromagnetically during the interval of the passage of the contrast medium. The measurements were performed in a model circulation and during coronary revascularization. From these examinations, the systematic deviation between electromagnetic and densitometric flow measurements was determined. In addition, the influence of the injected contrast medium on coronary artery flow was evaluated. The aim of this study was to establish the methodologic requirements for densitometric measurements of systolic and diastolic flow in the coronary artery system.

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mentioning

confidence: 99%

Measurement of systolic and diastolic flow rates in the coronary artery system by x-ray densitometry.

Spiller¹,

Schmiel²,

Pölitz³

et al. 1983

Circulation

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“…Gorlin and Storaasli (1956) firstly measured the transcoronary circulation time in man using the radioactive iodinated serum albumin. Benchimol et al (1971) measured instantaneous coronary artery blood flow rate by means of a catheter-tip ultrasonic flowmeter and investigated the effects of respiration and nitroglycerin on coronary circulation in man. Recently, Liedtke et al (1973) compared myocardial transit times in patients with and without coronary artery disease utilizing rapid injection of dye into the coronary artery and recording dye-dilution curve from the coronary sinus.…”

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confidence: 99%

Coronary Circulation Time in Man

Ishikawa

Haneda

Ikeda

et al. 1974

Tohoku J. Exp. Med.

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“…8 The method for obtaining such carotid artery blood flow velocity signals by radiotelemetry has been previously described in detail. 6 The Doppler ultrasonic method of measuring blood flow velocity has been applied to more than 1,000 subjects in the past four years in order to study coronary, 9 renal, 10 superior mesenteric, 11 and aortic blood flow velocity 12 under a variety of clinical and experimental conditions. Right carotid artery flow velocity, lead II of the electrocardiogram, tricuspid area phonocardiograms and at times apexcardiograms, external carotid pulse tracings and right atrial or ventricular pressures were recorded simultaneously.…”

Section: Methodsmentioning

confidence: 99%

The Effects of Ventricular Tachycardia on Carotid Artery Blood Flow Velocity

Benchimol

Baldi

Desser

1974

Stroke

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Abstract:The Effects of Ventricular Tachycardia on Carotid Artery Blood Flow Velocity• Utilizing the Doppler flowmeter catheter, right carotid blood velocity was measured during episodes of catheter-evoked and pacemaker-induced ventricular tachycardias. Such tachyarrhythmias uniformly diminished peak carotid blood velocity, which in the case of catheter-evoked episodes reduced phasic blood velocity by 50%. At driving rates greater than 140 per minute, the average peak carotid blood velocity was 25% to 50% lower during ventricular when compared with atrial pacing. There was a direct correlation between the ventricular pacing rates and the percent decline of peak carotid blood velocity. Such arrhythmiarelated carotid blood velocity deficits may account for syncopal episodes in subjects so affected.

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New method to measure phasic coronary blood velocity in man

Cited by 86 publications

References 20 publications

Measurement of systolic and diastolic flow rates in the coronary artery system by x-ray densitometry.

Measurement of systolic and diastolic flow rates in the coronary artery system by x-ray densitometry.

Coronary Circulation Time in Man

The Effects of Ventricular Tachycardia on Carotid Artery Blood Flow Velocity

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