Coronary Circulation Time in Man

Ishikawa, Kinji; Haneda, Takashi; Ikeda, Shigeyuki; Tsuiki, Kai; Miyazawa, Keiji; Katori, Ryo

doi:10.1620/tjem.114.253

Cited by 2 publications

(2 citation statements)

References 19 publications

(14 reference statements)

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“…This is approximately the time that the blood must travel from the coronary artery to the coronary vein. 16 The same happens in Figure 3, where a second peak appears near 26 seconds that is 10 seconds after the peak of aorta perfusion (the peak occurred around 16 seconds). The time difference indicates that the additional perfusion appearing in Figures 3 and 4 can be derived from CP-CA.…”

Section: Discussionsupporting

confidence: 54%

“…In CP-CA, it takes approximately 8 6 2 seconds to go from the coronary artery to the coronary vein. 16 However, the subject can hold his/her breath for a limited time and starts breathing before coronary circulation is observed in the lung. Therefore, it is inferred that the acquisition of the contribution from CP-CA was interrupted, causing an overestimation of blood perfusion in the pulmonary artery.…”

Section: Difference Between Left and Right Cardiac Outputmentioning

confidence: 99%

See 1 more Smart Citation

Phantom-Less Nonlinear Magnetic Resonance Imaging Calibration With Multiple Input Blood Flow Model

Saka

Gotoh

Kagei

et al. 2023

Topics in Magnetic Resonance Imaging

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Previous work used phantoms to calibrate the nonlinear relationship between the gadolinium contrast concentration and the intensity of the magnetic resonance imaging signal. This work proposes a new nonlinear calibration procedure without phantoms and considers the variation of contrast agent mass minimum combined with the multiple input blood flow system. This also proposes a new single-input method with meaningful variables that is not influenced by reperfusion or noise generated by aliasing. The reperfusion in the lung is usually neglected and is not considered by the indicator dilution method. However, in cases of lung cancer, reperfusion cannot be neglected. A new multiple input method is formulated, and the contribution of the pulmonary artery and bronchial artery to lung perfusion can be considered and evaluated separately. Methods:The calibration procedure applies the minimum variation of contrast agent mass in 3 different regions: (1) pulmonary artery, (2) left atrium, and (3) aorta. It was compared with four dimensional computerized tomography with iodine, which has a very high proportional relationship between contrast agent concentration and signal intensity.Results: Nonlinear calibration was performed without phantoms, and it is in the range of phantom calibration. It successfully separated the contributions of the pulmonary and bronchial arteries. The proposed multiple input method was verified in 6 subjects with lung cancer, and perfusion from the bronchial artery, rich in oxygen, was identified as very high in the cancer region.Conclusions: Nonlinear calibration of the contrast agent without phantoms is possible. Separate contributions of the pulmonary artery and aorta can be determined.

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Section: Discussionsupporting

confidence: 54%

Section: Difference Between Left and Right Cardiac Outputmentioning

confidence: 99%