New Luminescent Europium(III) Chelates for DNA Labeling

Nishioka, Takuya; Yuan, Jingli; Yamamoto, Yuji; Sumitomo, Keiko; Wang, Zhen; Hashino, Kimikazu; Hosoya, Chihiro; Ikawa, Keisuke; Wang, Guilan; Matsumoto, Kazuko

doi:10.1021/ic0615574

Cited by 14 publications

(17 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Rare earth complexes are attracting considerable attention on account of their rapidly growing number of applications, which include the development of fluorescence materials , electroluminescence devices and fluorescence probes and labels in a variety of biological systems . These application rely on the outstanding luminescence properties of rare‐earth complexes .…”

Section: Introductionmentioning

confidence: 99%

Synthesis, characterization and luminescent properties of europium complexes with 2,4,6‐tris‐(2‐pyridyl)‐s‐triazine as highly efficient sensitizers

et al. 2015

View full text Add to dashboard Cite

Using 2,4,6-tris-(2-pyridyl)-s-triazine (TPTZ) as a neutral ligand, and p-hydroxybenzoic acid, terephthalic acid and nitrate as anion ligands, five novel europium complexes have been synthesized. These complexes were characterized using elemental analysis, rare earth coordination titrations, UV/vis absorption spectroscopy and infrared spectroscopy. Luminescence spectra, luminescence lifetime and quantum efficiency were investigated and the mechanism discussed in depth. The results show that the complexes have excellent emission intensities, long emission lifetimes and high quantum efficiencies. The superior luminescent properties of the complexes may be because the triplet energy level of the ligands matches well with the lowest excitation state energy level of Eu(3+). Moreover, changing the ratio of the ligands and metal ions leads to different luminescent properties. Among the complexes, Eu2(TPTZ)2(C8H4O4)(NO3)4(C2H5OH)·H2O shows the strongest luminescence intensity, longest emission lifetime and highest quantum efficiency.

show abstract

Section: Introductionmentioning

confidence: 99%

Synthesis, characterization and luminescent properties of europium complexes with 2,4,6‐tris‐(2‐pyridyl)‐s‐triazine as highly efficient sensitizers

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Some lanthanide complexes as probes for DNA have been proposed. [4,[10][11][12] At the same time, studies show that some lanthanide complexes might have a potential role in the treatment of tumor cell lines, [13] so the design and synthesis of the lanthanide complexes as potential anticancer and antibacterial agents have received more attention. [14] In these complexes, tremendous interest has been attracted to the lanthanide complexes with organic ligands [15,16] because of the metal or ligands can be varied in an easily controlled way to facilitate the individual applications.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Biological Studies of Some Lanthanide Complexes of Schiff Base

Chu

Shi

et al. 2015

Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-

View full text Add to dashboard Cite

Four new solid ternary complexes of lanthanide with Schiff base (isoniazid furalacylhydrazone) and sodium salicylate [Ln(FLSY) (Lin)(NO 3 )] NO 3 ¢H 2 O (Ln D La, Ce, Nd, Er; FLSY D isoniazid furalacylhydrazone; Lin D sodium salicylate) have been synthesized and characterized by elemental analysis, FT-IR, UV-Vis, 1 H NMR, TG-DTA, and XPS. The antibacterial activities test indicate that all the complexes exhibit moderate antibacterial ability against Escherichia coli and Staphylococcus aureus with broad antimicrobial spectrums. The cytotoxic activity of the complexes has been tested by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) method. The complexes can effectively inhibit the proliferation of K562 tumor cells. The authors investigate the interactions of the Er complex with calf-thymus DNA (CT DNA) employing florescence spectroscopic studies, cyclic voltammetric experiment, ultraviolet spectrum studies, and photoactivated cleavage. DNA interaction studies suggest the Er complex can intercalate between DNA base pairs and the complex can photocleave pBR322 DNA in vitro.

show abstract

“…The luminescence of rare‐earth (RE) organic complexes has narrow emission bands and high luminous intensity. It has been used in many areas, such as fluorescence materials , electroluminescence devices , fluorescence probes and labels in a variety of biological systems . Usually the intra‐configuration 4f–4f transitions in rare‐earth ions are forbidden (Laporte rule).…”

Section: Introductionmentioning

confidence: 99%

Fluorescence emission mechanism and fluorescence properties of ternary Tb(III) complex with diphenyl sulphoxide and bipyridine

Zheng

Chai

et al. 2011

Luminescence

View full text Add to dashboard Cite

A novel ternary complex, TbL(5) L'(ClO(4))(3) · 3H(2)O, two binary complexes, TbL(7) (ClO(4))(3) · 3H(2)O and TbL'(3.5) (ClO(4))(3) · 4H(2)O has been synthesized (using diphenyl sulphoxide as the first ligand L, bipyridine as the second ligand L'). Their composition was analysed by element analysis, coordination titration, IR spectra and (1) H-NMR, and the fluorescence emission mechanism, fluorescence intensities and phosphorescence spectra were also investigated by comparison. It was shown that the ternary rare-earth complex showed stronger fluorescence intensities than the binary rare-earth complexes in such material. The strongest characteristic fluorescence emission intensity of the ternary system was 8.23 times, 3.58 times as strong as that of the binary systems TbL(7) (ClO(4))(3) · 3H(2)O and TbL'(3.5) (ClO(4))(3) · 4H(2)O, respectively. By fluorescence analysis it was found that both diphenyl sulphoxide and bipyridine could sensitize the fluorescence intensities of rare-earth ions. In particular, in the ternary rare-earth complex, introduction of bipyridine was of benefit to the fluorescence properties of Tb(III).

show abstract

New Luminescent Europium(III) Chelates for DNA Labeling

Cited by 14 publications

References 0 publications

Synthesis, characterization and luminescent properties of europium complexes with 2,4,6‐tris‐(2‐pyridyl)‐s‐triazine as highly efficient sensitizers

Synthesis, characterization and luminescent properties of europium complexes with 2,4,6‐tris‐(2‐pyridyl)‐s‐triazine as highly efficient sensitizers

Synthesis and Biological Studies of Some Lanthanide Complexes of Schiff Base

Fluorescence emission mechanism and fluorescence properties of ternary Tb(III) complex with diphenyl sulphoxide and bipyridine

Contact Info

Product

Resources

About