New insights into treatment of children with exercise-induced asthma symptoms

Stelmach, Iwona; Sztafiska, Anna; Jerzyska, Joanna; Podlecka, Daniela; Majak, Paweł; Stelmach, Wodzimierz

doi:10.2500/aap.2016.37.3993

Cited by 10 publications

(13 citation statements)

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“…16 In addition, PA has the role of improving physical fitness in childhood, which is essencial for the maintenance of physical fitness in adulthood, as well as improving psychological, social and therapeutic aspects, and reducing wheezing, hospitalization, and even the use of medication for asthma. 12 Despite the benefits of physical training for asthmatics, [13][14] physical exercise has the potential to induce bronchospasm. [18][19] Studies conducted in different populations, with children, adolescents and adults, have shown that some effects of physical training can be proven in asthmatics, such as improving cardiorespiratory fitness and tolerance to the effort, as well as reducing exercise dyspnea, aerobic fitness and quality of life.…”

Section: Discussionmentioning

confidence: 99%

“…5 Individuals with controlled asthma and no history of EIB can perform physical activity without restriction. 12 However, asthmatics with EIB should prioritize moderate-intensity exercise, between 40 to 59% of VO 2max or 55 to 69% of HR max , so to avoid the triggering of EIB. 18 Besides that, the use of bronchodilators is recommended for asthmatic individuals with a history of EIB who intend to exercise at higher intensities.…”

Section: Discussionmentioning

confidence: 99%

“…10 Although exercise is a triggering agent of bronchospasm, regular physical activity is considered an important component in the treatment of asthma. 12 The systematic reviews and meta-analyzes conducted so far have reported that physical training in young asthmatics was able to increase cardiorespiratory fitness 13,14 and reduce exercise dyspnea, 15,16 as well as improve quality of life. 16,17 .…”

Section: Introductionmentioning

confidence: 99%

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Effect of Physical Training on Exercise-Induced Bronchospasm in Young Asthmatics

Lopes

Porto

Leite³

2020

Rev Bras Med Esporte

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Introduction: Asthma is the most common chronic disease in childhood and its prevalence has increased in recent years. Although regular physical activity (PA) is considered to be beneficial for the health of asthmatics, especially children and adolescents, it can also be one of the elements that triggers asthma. This is known as exercise-induced bronchospasm (EIB), and is considered one of the factors that limits asthmatics’ participation in PA. Objective: This study aims to review the effects of physical conditioning on EIB in asthmatic children and adolescents. Methods: A systematic review was carried out on the Pubmed, Bireme and Web of Science databases, considering publications from 1998 to April 2019. Results: Eight articles were retrieved; five of the articles presented no significant difference in EIB parameters after physical training, and three demonstrated significant benefits in EIB. Conclusion: There is insufficient evidence that physical training helps reduce the frequency and severity of EIB in young asthmatics. There are still few studies that seek to show the effect of a physical training program on the improvement of EIB in children and adolescents. It is suggested that further randomized clinical trials be conducted, to investigate the effects of physical training on EIB parameters in children and adolescents. Level of Evidence II; Systematic review.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Effect of Physical Training on Exercise-Induced Bronchospasm in Young Asthmatics

Lopes

Porto

Leite³

2020

Rev Bras Med Esporte

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“…All pulmonary function tests were performed with a Master Screen unit (Erich Jaeger Gmbh-Hochberg, Germany), as described elsewhere, in accordance with the ATS/ERS guidelines (15,16). The highest of 3 successful measurements of spirometry was taken and analysed.…”

Section: Lung Function Body Plethysmography (Srtot Rocc)mentioning

confidence: 99%

Allergic rhinitis and house dust mite sensitization determine persistence of asthma in children.

Brzozowska

Woicka-Kolejwa

Jerzyńska

et al. 2020

Preprint

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Background: MAS study revealed that chronic course of asthma characterised by airway hyper-responsiveness and impairment of lung function at school age is determined by continuing allergic airway inflammation which begin in the first 3 years of life. Respiratory tract infections early in life, childhood allergic comorbidities, exposure to environmental determinants of asthma and active smoking may all contribute to increased risk of allergic disorders. While these correlations have been established, there is little understanding of the immunological mechanisms by which asthma develops into a persistent disease, or by which symptoms regress. Methods: Eighty patients were included into the analysis. Clinical and immunoregulatory predictors of asthma were analyzed. Results: Presence of mAPI criteria as well as the presence of house dust mite-allergy and allergic rhinitis at present, were associated with a reduced prevalence of asthma remission. The presence of increased eosinophil blood count in API (Asthma Predictive Index) criteria was associated with a lower expression of CD25 positive cells. Current presence of HDM-allergy was associated with a higher FeNO level and higher expression of CD25CD71 positive cells. Allergic rhinitis was associated with a higher expression of PPAR and CD25CD71 positive cells; in the same group of patients a lower expression of GARP positive cells were observed. Conclusions: Probability of persistence of childhood asthma was largely determined by the presence of allergic rhinitis and sensitization to HDM. Our results suggest natural remission of clinical symptoms of asthma in children are not fully related to immunoregulation processes. Additionally, API criteria are related to asthma persistence.

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“…Individualizing therapy for more challenging cases of exercise-induced bronchospasm requires further investigation. To this end Stelmach et al 12 report the results of a randomized, double-blind, placebo-controlled clinical trial to assess the relative effectiveness of ciclesonide 160 g treatment either alone or at a higher dose, or with a leukotriene receptor antagonist, or with a long-acting ␤2agonist in children after exercise-induced asthma symptoms.…”

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confidence: 99%

A Janus tale of the two faces of corticosteroid therapy: A potential for adverse effects versus a steroid-sparing benefit of certain therapies

Bellanti¹,

Settipane²

2016

allergy asthma proc

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New insights into treatment of children with exercise-induced asthma symptoms

Cited by 10 publications

References 0 publications

Effect of Physical Training on Exercise-Induced Bronchospasm in Young Asthmatics

Effect of Physical Training on Exercise-Induced Bronchospasm in Young Asthmatics

Allergic rhinitis and house dust mite sensitization determine persistence of asthma in children.

A Janus tale of the two faces of corticosteroid therapy: A potential for adverse effects versus a steroid-sparing benefit of certain therapies

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