New focus of active transmission of Chagas disease in indigenous populations in the Peruvian Amazon basin

Cabrera, Rufino; Vega, Silvia; Valderrama, Yadira; Cabanillas, Karina; Fernández, Connie; Rodríguez, O Afonso; Aguila, César Del; Hernández, Jesús; Mendoza, Leonardo; Meza, Juan Ramón

doi:10.1590/0037-8682-1195-2013

Cited by 8 publications

(18 citation statements)

References 6 publications

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“…It is important to implement measures for controlling transmission of T. cruzi by triatomines in the Amazon basin, with vector surveillance and control with insecticide as has been happening in other parts of Peru ( 5 ). In light of our exploratory results and other cases reported in the area, it could be of interest to perform similar studies to those carried out in other parts of Peru ( 15 , 17 , 23 ). Another topic to investigate in the area is dogs, which are important reservoirs of T. cruzi and may play a role in reinitiating transmission in previously sprayed areas.…”

Section: Discussionsupporting

confidence: 68%

“…The presence of pregnant women in the Amazon Basin who are at risk of congenital transmission to the fetus, along with other reported cases of acute Chagas Diseases ( 6 , 16 , 17 ) should serve as a warning of an (emerging) problem in this area of Peru. While the low prevalence does not justify screening in pregnant or puerperal women, other measures are called for.…”

Section: Discussionmentioning

confidence: 99%

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Chagas Disease in Pregnant Women in the Peruvian Amazon Basin. Cross-Sectional Study

et al. 2020

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Aims: To assess the prevalence of Chagas disease in pregnant women in Iquitos City, Peru. Material and Methods: Cross-sectional survey in 300 pregnant women in Iquitos (Peru) from 1 May 2019 to 15 June 2019. Women were tested using an ELISA serology test. Results: Serology was positive in one case (prevalence: 0.33%; 95% confidence interval: 7.1–13.9%), of a 25-year-old woman who lived in a wooden house with a leaf roof in a periurban area of Iquitos. She was familiar with kissing bugs and had chronic, asymptomatic Chagas disease. Conclusion: The prevalence of Chagas disease is low in the urban and peri-urban area of the city of Iquitos.

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Section: Discussionsupporting

confidence: 68%

Section: Discussionmentioning

confidence: 99%

Chagas Disease in Pregnant Women in the Peruvian Amazon Basin. Cross-Sectional Study

et al. 2020

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“…The Mayuriaga village that was evaluated in our study also reported a case of human Chagas disease. 37 Future studies will assist to develop strategies for prevention, control, and diagnosis of American trypanosomiasis in the Peruvian Amazon Basin which presents a new and a different scenario for Chagas disease in Peru, where populations often live in remote and isolated locations with serious health-care access limitations.…”

Section: Discussionmentioning

confidence: 99%

First Report of Trypanosoma cruzi Infection in Salivary Gland of Bats from the Peruvian Amazon

Villena

Gómez-Puerta

Jhonston

et al. 2018

The American Journal of Tropical Medicine and Hygiene

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Abstract.In the Americas, 8 million people are infected with Chagas disease, and an additional 90 million people are at risk for infection. Little is known about the role bats play in the sylvatic transmission cycle of Trypanosoma cruzi, the parasite causing Chagas disease. Here, we captured bats in the villages of Palmiche, Pachacutec, Nuevo San Martin, and Mayuriaga located in the Datem del Marañon Province in Loreto, Peru. Venous blood samples were collected by cardiac puncture or from the upper extremities, and trypanosomatids were identified by microscopy and molecularly. We collected blood samples from 121 bats on filter paper for molecular studies and 111 slides for microscopic examination of thin and thick blood smears from 16 different bat species. The prevalence of trypanosomatids in all bats species was 34.7% (42/121) and the prevalence of T. cruzi was 4.1% (5/121). In hematophagous bat species, the prevalence of trypanosomatids and T. cruzi was 36.9% (27/73) and 2.7% (2/73), respectively. In non-hematophagous bats, the prevalences of trypanosomatids and T. cruzi were 31.2% (15/48) and 6.2% (3/48), respectively. Also, we confirm the presence of T. cruzi in salivary glands of hematophagous bats Diaemus youngi. These results suggest a sylvatic cycle of trypanosomatid transmission in which bats may harbor infectious T. cruzi parasites that could be transmitted to humans via hematophagous bat bites or salivary contamination by non-hematophagous bats of vegetables consumed by humans.

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“…In Peru, the first ACD case was reported in 1919 in the southeastern Amazonian department of Madre de Dios. Only a few ACD cases have been reported since, although multiple cases have been reported in recent years in Amazonian regions such as Pasco and Loreto [19]. In Ecuador, Chagas disease was first diagnosed in 1929 in Guayas, a coastal province.…”

Section: Chagas Disease Transmission In the Amazon Basinmentioning

confidence: 99%

“…During 2006 to 2010, six ACD cases were reported among children from the Aguaruna, Huambisa and Kandoshi communities in the Peruvian Amazon basin. ACD was attributed to either the biting of infected triatomines found inside the dwellings or oral transmission by drinking "masato" (a fermented beverage made with yuca) or "chapo" (a ripe banana beverage) since no traveling outside the community or blood transfusion was recorded [19]. ACD cases in indigenous communities in Ecuador Amazon region have been reported since 1987; a seroepidemiological study found a 6.0% (61/1011) of positive individuals from 15 of the 18 studied communities.…”

Section: Chagas Disease Transmission In the Amazon Basinmentioning

confidence: 99%

Amazonian Reservoir Hosts of Trypanosoma cruzi

Lazo¹,

Mayor²,

Lescano³

2019

Biology of Trypanosoma Cruzi

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The epidemiology of Trypanosoma cruzi in the wild is a particular and highly dynamic scenario that needs attention due to the increased alteration of the environment caused by different factors including anthropogenic change. This chapter is an updated summary about the known reservoir hosts of T. cruzi identified in the countries that share the Amazon rainforest. This information will provide a better understanding of the ecology of T. cruzi in sylvatic environments. This chapter will also contribute to address the potential risks of T. cruzi infection in Amazonian communities who are in contact with wild animals through hunting and wild meat consumption.

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New focus of active transmission of Chagas disease in indigenous populations in the Peruvian Amazon basin

Cited by 8 publications

References 6 publications

Chagas Disease in Pregnant Women in the Peruvian Amazon Basin. Cross-Sectional Study

Chagas Disease in Pregnant Women in the Peruvian Amazon Basin. Cross-Sectional Study

First Report of Trypanosoma cruzi Infection in Salivary Gland of Bats from the Peruvian Amazon

Amazonian Reservoir Hosts of Trypanosoma cruzi

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