Chagas Disease in Pregnant Women in the Peruvian Amazon Basin. Cross-Sectional Study

Abstract

Aims: To assess the prevalence of Chagas disease in pregnant women in Iquitos City, Peru. Material and Methods: Cross-sectional survey in 300 pregnant women in Iquitos (Peru) from 1 May 2019 to 15 June 2019. Women were tested using an ELISA serology test. Results: Serology was positive in one case (prevalence: 0.33%; 95% confidence interval: 7.1–13.9%), of a 25-year-old woman who lived in a wooden house with a leaf roof in a periurban area of Iquitos. She was familiar with kissing bugs and had chronic, asymptomatic Chagas disease. Conclusion: The prevalence of Chagas disease is low in the urban and peri-urban area of the city of Iquitos.

Analysis of the Chagas disease situation in Japan: a cross sectional study and cost-effectiveness analysis of a Chagas disease screening program

“… 12 , 13 , 38 Secondly, due to the low endemicity in Sao Paulo and Lima, the main districts of origin of Brazilians and Peruvian respectively, a larger number of participants would be necessary to showcases. 39 , 40 , 41 , 42 The results showed that the screening is cost-effective until a prevalence of 0.43%, supporting the inclusion of Bolivians and Peruvians. On the other hand, a country base screening has several disadvantages.…”

Antígeno nativo y no nativo para determinar la seroprevalencia de Trypanosoma cruzi en mujeres embarazadas en el estado de Morelos, México

“…Ramos-Rincón y cols., en su estudio sobre la EC en mujeres embarazadas de la Cuenca Amazónica Peruana utilizaron dos estuches comerciales: Chagatest ELISA con lisado de T. cruzi (Weiner, Rosario, Argentina) y Chagatest ELISA recombinante (Weiner, Rosario, Argentina), detectaron 4 casos positivos por ELISA recombinante, de los cuales sólo uno resultó positivo por ELISA que utilizó lisado, y 3 muestras como no concluyentes. Reportaron una seroprevalencia de anticuerpos anti-T. cruzi de 0,33% 31 , muy similar a lo reportado en el presente estudio al utilizar las 3 pruebas serológicas en serie (0,43%).…”

Cribaje de la enfermedad de Chagas en la amazonia peruana

“…No obstante, no contamos con estudios epidemiológicos concluyentes. En un estudio reciente realizado en 300 mujeres embarazadas publicado por nuestro grupo, se identificó una paciente con la enfermedad asintomática (5) .…”

“…However, we do not have conclusive epidemiological studies. In a recent study of 300 pregnant women published by our group, one patient with asymptomatic disease was identified 5 .…”