A new section Salsuginosae in the genus Potentilla is described based on morphological characteristics and ecological confinement. It contains P. laevipes and P. laevissima, two rarest endemics of the Altai Mountainous Country, known from collections only from Western Mongolia. For the representatives of the new section, for the first time, data on the genome size and chromosome numbers were revealed, information on morphology and distribution was supplemented, and a conservation status was proposed. Photos of P. laevissima in its natural habitat are provided, for the first time. Most of the studied herbarium samples were scanned and are provided in the Global Biodiversity Information Facility (GBIF.org).