New Epigallocatechin Gallate (EGCG) Nanocomplexes Co-Assembled with 3-Mercapto-1-Hexanol and <i>β</i>-Lactoglobulin for Improvement of Antitumor Activity

Yang, Yuanyuan; Jin, Peng; Zhang, Xingcai; Ravichandran, Nagaiya; Hao, Ying; Yu, Chenghuan; Ying, Hua‐Zhong; Xu, Yong-Quan; Yin, Jun-Feng; Wang, Kai; Wu, Ming; Du, Qizhen

doi:10.1166/jbn.2017.2400

Cited by 69 publications

(28 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nanotechnology is the study of phenomena and manipulation of materials at atomic, molecular and macromolecular scale. It is a rapidly growing field with its wide application in science and technology for manufacturing of new materials at nanoscale level [1]. It includes the synthesis, characterization, exploration and utilization of nanostructured materials.…”

Section: Introductionmentioning

confidence: 99%

Chemical Synthesis of Silver Nanoparticles Using Tri-sodium Citrate, Stability Study and Their Characterization

Yerragopu

Hiregoudar

Nidoni

et al. 2020

IRJPAC

View full text Add to dashboard Cite

The present work was aimed to study the synthesis of silver nanoparticles (Ag NPs) using Tri-Sodium Citrate (TSC), stability study of synthesized Ag NPs and their characterization. Synthesis of Ag NPs has been carried out by maintaining different conditions such as TSC concentration (0.50, 1.00 and 1.50%), AgNO3 concentration (0.50, 1.00 and 1.50 mM) and stirring time (10, 15 and 20 min). The stability study of synthesized Ag NPs conducted for 30 days without adding any stabilizing agents. The characterization of synthesized Ag NPs was carried out for different parameters like particle size and zeta potential using particle size analyzer, absorbance peak by UV-Visible spectrophotometer, morphology by Scanning Electron Microscope (SEM), crystallinity by X-Ray Diffractometer (XRD) and material structural characteristics by Atomic Force Microscope (AFM). The stable chemically synthesized Ag NPs were obtained at C20 (AgNO3 concentration of 1.5 mM, TSC 1.5% and stirring time 20 min) (desirability 99.97%), with average particle size of 22.14 nm and average absorbance peak of 449.85 nm.

show abstract

Section: Introductionmentioning

confidence: 99%

Chemical Synthesis of Silver Nanoparticles Using Tri-sodium Citrate, Stability Study and Their Characterization

Yerragopu

Hiregoudar

Nidoni

et al. 2020

IRJPAC

View full text Add to dashboard Cite

show abstract

“…Among the different metal nanoparticles (MNPs), zinc oxide nanoparticles (ZnONPs) has received due attention due to their multifunctional and tunable nature. ZnONPs possess 3.37 eV direct band gap with high excitation energy (60 meV), which make it perfect to be utilized in UV photodetector, transistors, and semiconductor diodes [6][7][8]. In addition, ZnONPs are used in the field of bio-imaging, drug delivery, mineral based sunscreens, lotions, and ointments; biomedicine, especially in the fields of anticancer and antibacterial fields, which are involved with their potent ability to trigger excess reactive oxygen species (ROS) production, release zinc ions, and induce cell apoptosis [9].…”

Section: Introductionmentioning

confidence: 99%

Bioactivities of Geranium wallichianum Leaf Extracts Conjugated with Zinc Oxide Nanoparticles

et al. 2019

View full text Add to dashboard Cite

This study attempts to obtain and test the bioactivities of leaf extracts from a medicinal plant, Geranium wallichianum (GW), when conjugated with zinc oxide nanoparticles (ZnONPs). The integrity of leaf extract-conjugated ZnONPs (GW-ZnONPs) was confirmed using various techniques, including Ultraviolet–visible spectroscopy, X-Ray Diffraction, Fourier Transform Infrared Spectroscopy, energy-dispersive spectra (EDS), scanning electron microscopy, transmission electron microscopy, and Raman spectroscopy. The size of ZnONPs was approximately 18 nm, which was determined by TEM analysis. Additionally, the energy-dispersive spectra (EDS) revealed that NPs have zinc in its pure form. Bioactivities of GW-ZnONPs including antimicrobial potentials, cytotoxicity, antioxidative capacities, inhibition potentials against α-amylase, and protein kinases, as well as biocompatibility were intensively tested and confirmed. Altogether, the results revealed that GW-ZnONPs are non-toxic, biocompatible, and have considerable potential in biological applications.

show abstract

“…Although numerous metals exist in nature, only a few of them such as iron, silver, gold, tin and platinum are synthesized extensively in nanostructured form . Among these metals, iron oxide (IO)NPs have potentially gained the attention of the scientific community due to their unique properties and potential applications in biomedicine, diagnostics, therapeutics, bioremediation, cosmetics and materials engineering .…”

Section: Introductionmentioning

confidence: 99%

Biofabrication of iron oxide nanoparticles by leaf extract of Rhamnus virgata: Characterization and evaluation of cytotoxic, antimicrobial and antioxidant potentials

Abbasi

Iqbal

Mahmood

et al. 2019

Applied Organom Chemis

View full text Add to dashboard Cite

In the present study, plant‐mediated synthesis of iron oxide nanoparticles (IONPs) using leaves extract of Rhamnus virgata (Roxb.) as a potential stabilizing, reducing and chelating agent is reported. The biogenic IONPs are extensively characterized for their physical and biological properties. The morphology, structure and physicochemical properties of biogenic IONPs were characterized using ultraviolet spectroscopy, X‐ray diffraction, Fourier transform‐infrared analysis, scanning electron microscopy, energy‐dispersive spectroscopy, transmission electron microscopy, Raman spectroscopy and dynamic light scattering. The Scherrer equation deduced a mean crystallite size of ~20 nm for IONPs. Detailed in vitro biological activities revealed significant therapeutic potentials for IONPs. Potential antibacterial and antifungal activities are reported for IONPs. Bioinspired IONPs have shown potential results against HepG2 cells (IC50: 13.47 μg/ml). Dose‐dependent cytotoxicity assays were revealed against Leishmania tropica (KMH23) promastigotes (IC50: 8.08 μg/ml) and amastigotes (IC50: 20.82 μg/ml) using different concentrations of IONPs (1–200 μg/ml). The cytotoxic activity was also studied using brine shrimps, and their IC50 value was calculated as 32.41 μg/ml. Significant antioxidant [TAC (51.4%), DPPH (79.4%) and total reducing power (62%)], protein kinase and alpha amylase inhibition assays were revealed. The biocompatibility assays using red blood cells (> 200 μg/ml) and macrophages (> 200 μg/ml) confirmed the biosafe nature of IONPs. In conclusion, bioinspired IONPs have shown potential biological applications and should be subjected to further research work to develop their nano‐pharmacological relevance in biomedical applications.

show abstract

New Epigallocatechin Gallate (EGCG) Nanocomplexes Co-Assembled with 3-Mercapto-1-Hexanol and β-Lactoglobulin for Improvement of Antitumor Activity

Cited by 69 publications

References 0 publications

Chemical Synthesis of Silver Nanoparticles Using Tri-sodium Citrate, Stability Study and Their Characterization

Chemical Synthesis of Silver Nanoparticles Using Tri-sodium Citrate, Stability Study and Their Characterization

Bioactivities of Geranium wallichianum Leaf Extracts Conjugated with Zinc Oxide Nanoparticles

Biofabrication of iron oxide nanoparticles by leaf extract of Rhamnus virgata: Characterization and evaluation of cytotoxic, antimicrobial and antioxidant potentials

Contact Info

Product

Resources

About