This article gives an overview of fluorochlorozirconate glass-ceramic scintillators and storage phosphor materials: how they are synthesized, what their properties are, and how they can be used in medical imaging. Such materials can enhance imaging in x-ray radiography, especially mammography and dental imaging, computed tomography, and positron emission tomography. Although focusing on fluorochlorozirconate materials, the reader will find the discussion is relevant to other luminescent glass and glass-ceramic systems.