New dental findings in the median cleft facial syndrome

Tooth abnormalities and soft tissue alterations in patients with G/BBB syndrome

“…It is agreed that the syndrome is originated from a developmental defect of the midline field (Cappa et al , 1987) and virtually all anomalies in this syndrome represent midline defects (Opitz, 1987). Interestingly, the presence of a supernumerary mandibular incisor was reported in a patient with frontonasal dysplasia, which also constitutes a midline defect (Haro Montero et al , 2005). Thus, the frequent observation of incisiform supernumerary teeth in the mandibular anterior region may also constitute a midline defect and, based on these findings, might be included among the characteristics of the syndrome.…”