“…(2S,3S,5S,6S,7S,8R,11S,12R)-15-deacetyl-7,8dihydroxycalonectrin (334) and 1-methyl-4-[3,4,5-trihydroxy-1,2,2-trimethylcyclopently] benzene (335) (Figure 7) were isolated from the deep-sea-derived Penicillium sp. LXY140-R. 1-methyl-4-[3,4,5-trihydroxy-1,2,2-trimethylcyclopently] benzene (335) showed potent antiproliferative activity against HCT-116 cell lines with an IC 50 value of 124.12 µM [97]. Nor-bisabolane derivative enantiomers (±)-1 (336a/b) (Figure 7) were isolated from the algal-derived P. chrysogenum LD-201810 [98].…”