New coumarins and anti-inflammatory constituents from Zanthoxylum avicennae

Cho, Jui Ying; Hwang, Tsong‐Long; Chang, Tsun-Hsu; Lim, Yun Ping; Sung, Ping Jyun; Lee, Tzong‐Huei; Chen, Jih Jung

doi:10.1016/j.foodchem.2012.04.025

Cited by 43 publications

(19 citation statements)

References 30 publications

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“…Wang et al extracted leaves of 11 bamboo species and determined 12 coumarin derivatives [17]. Coumarins with anti-inflammatory properties were isolated from the leaves of Zanthoxylum schinifolium [18] and Zanthoxylum avicennae [19]. Monoterpene coumarins, with major cytotoxic activity against Leishmania major, were isolated from Micromelum minutum leaves by Sakunpak et al [20].…”

Section: Introductionmentioning

confidence: 99%

Recent Advances in the Synthesis of Coumarin Derivatives from Different Starting Materials

et al. 2020

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The study of coumarin dates back to 1820 when coumarin was first extracted from tonka bean by Vogel. Compounds containing coumarin backbone are a very important group of compounds due to their usage in pharmacy and medicine. Properties and biological activities of coumarin derivatives have a significant role in the development of new drugs. Therefore, many different methods and techniques are developed in order to synthesize coumarin derivatives. Coumarin derivatives could be obtained from different starting materials with various methods but with big differences in yield. This review summarized various methods, techniques and reaction conditions for synthesis of coumarins from different compounds such as aldehydes, phenols, ketones and carboxylic acids.

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Section: Introductionmentioning

confidence: 99%

Recent Advances in the Synthesis of Coumarin Derivatives from Different Starting Materials

et al. 2020

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“…It is distributed mainly in dry forests, thickets and on open slopes at an altitude of up to 1630 metres above sea level, in India, China, Taiwan, and South East Asia (Hartley, 1966;Liu et al, 2014;Dai, et al, 2012). For a long time, Z. avicenna was used traditionally for various purposes in some regions, such as an important folk medicine for rheumatism, abdominal pain, jaundice, chronic hepatitis and the common cold in China (Cho et al, 2012, , Liu et al, 2014, as spices and flavouring agents in South East Asia (Seidemann, 2005;Cho et al, 2012), and as a digestive tonic in Vietnam (Chi, 1997).…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Activity of the Essential Oil of Zanthoxylum Avicennae

Andila¹

2019

BUM

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Minyak atsiri Zanthoxylum avicennae (Lam.) DC diektrak dari organ daun dan buah tanaman koleksi Kebun Raya “Eka Karya” Bali. Spesies ini dikoleksi dari Nusa Tenggara Barat pada 15 Juni 1993, dan kemudian di tanam di Kebun Raya “Eka Karya” Bali sejak 15 Desember 1993. Tujuan dari penelitian ini adalah untuk menggali sifat antibakteri dan antifungi dari minyak atsiri daun dan buah Z. avicennae. Untuk pengujian antimikroba, kedua minyak atsiri diuji dengan lima jamur patogen tanaman, yaitu Fusarium oxysforum(+), F. solani(+), Aspergilus niger(+), Collectotricum sp.(+), and Cladosporium sp. dan empat bakteri manusia yaitu Eschericia coli ATCC 43894, Salmonella typhimurium, E. coli (strain isolasi klinis), dan Staphylococcus aureus. Hasil penelitian mengungkapkan bahwa kedua minyak atsiri Z. avicennae (Minyak daun dan Buah) memiliki aktivitas antifungi yang kuat terhadap kelima jamur uji. Untuk uji antibakteri, Minyak atsiri daun menunjukkan hasil positif aktivitas antibacteri terhadap Eschericia coli, tetapi tidak terhadap bakteri Staphylococcus aureus. Sedangkan minyak atsiri buah menunjukkan hasil positive aktivitas antibakteri terhadap Shalmonella thipymurium and Eschericia coli atcc 43894. Kata kunci : Zanthoxylum avicennae, jamur patogen tanaman, bakteri, minyak atsiri; antimikroba.

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“…The chemical constituents of this medicinal herb have been studied. Alkaloids, coumarins, terpenoids, flavonoids, and neolignans, and their derivatives were isolated from this plant in previous studies [8][9][10][11][12][13]. Chemical composition of the essential oil of Z. avicennae has also been determined [14][15][16].…”

Section: Introductionmentioning

confidence: 99%