New Briarane Diterpenes from a Gorgonacean Briareum sp.

Iwagawa, Tetsuo; Takayama, Keita; Okamura, Hiroaki; Nakatani, Munehiro; Doe, Matsumi

doi:10.3987/com-99-8533

Cited by 16 publications

(15 citation statements)

References 8 publications

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“…553 Mild inhibition of the release of human neutrophil elastase was observed for 635 and 637. The absolute configuration of violide E 643, isolated from Briareum sp., 557 has been secured by X-ray analysis of the bis-MTPA ester. 558 Xenia novaebrittanniae (Kitagamwa, Kenya) was the source of seven new Xenia-class diterpenes novaxenicins A-D 644-647 and xeniolides I-K 648-650.…”

Section: (+)-Cyanthiwiginmentioning

confidence: 99%

Marine natural products

et al. 2008

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This review covers the literature published in 2006 for marine natural products, with 758 citations (534 for the period January to December 2006) referring to compounds isolated from marine microorganisms and phytoplankton, green algae, brown algae, red algae, sponges, cnidaria, bryozoans, molluscs, tunicates and echinoderms. The emphasis is on new compounds (779 for 2006), together with their relevant biological activities, source organisms and country of origin. Biosynthetic studies, first syntheses, and syntheses that lead to the revision of structures or stereochemistries, have been included.

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Section: (+)-Cyanthiwiginmentioning

confidence: 99%

Marine natural products

et al. 2008

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“…42 Investigation of bioactive metabolites from a Briareum sp. collected in the area of Bonotsu, Kogoshima Prefecture, has led to the isolation of the briaranetype diterpenoids violides C-V (155)(156)(157)(158)(159)(160)(161)(162)(163)(164)(165)(166)(167)(168)(169)(170)(171)(172)(173)(174) and five new structures related to the violides (175-179), [43][44][45][46][47] their structures being elucidated by interpretation of spectroscopic and X-ray crystallographic data. Some of these metabolites exhibited moderate cytotoxicity against the growth of Vero and MDCK cells.…”

Section: Family Briareidaementioning

confidence: 99%

Diterpenes from gorgonian corals

2009

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Covering: 1995 to April 2008. Gorgonian corals continue to provide a wealth of novel structures, many of which exhibit potentially useful biological activity. Notably, the families Briareidae, Gorgoniidae and Plexauridae have been demonstrated to contain a wide variety of natural products including steroids, acetogenins, sesquiterpenes and diterpenes. The most common of the gorgonian natural products are the diterpenes, and the intent of this review is to describe such compounds isolated from gorgonian corals, with a focus on the structures of new compounds as well as their biological activity. There have been developments improving our understanding of the biosynthetic origin of selected diterpenes, and these will also be discussed. This review describes 602 new compounds from 177 articles.

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“…483 Erythropodium caribaeorum from Jamaica contained three additional briaranes, erythrolide E 3-acetate 665, erythrolide F 3-acetate 666 and erythrolide H 16-acetate 667. 484 Violides C-I 668-674 are additional briarane diterpenes from a Japanese species of Briareum (aka Pachyclavularai violacea): 485 the authors propose that two previously reported 486 analogs be renamed violides A and B. A subsequent paper reported the isolation of violides J -M 675-678 from the same organism and the X-ray crystallographic structure determination of violide J 675.…”

Section: Coelenteratesmentioning

confidence: 99%