New bioactive metabolites produced by Colletotrichum sp., an endophytic fungus in Artemisia annua

Lü, Hong; Zou, W. X.; Meng, Jun Cai; Hu, Jun; Tan, Ren Xiang

doi:10.1016/s0168-9452(99)00199-5

Cited by 279 publications

(167 citation statements)

References 15 publications

Supporting

Mentioning

141

Contrasting

Unclassified

Order By: Relevance

“…Afterwards it has been reported by strains of Colletotrichum sp. from Artemisia annua [17], Talaromyces verruculosus (=Penicillium verruculosum) from roots of Potentilla fulgens [18], and Penicillium glabrum from pomegranate (Punica granatum) fruits [19]. An isolate of the yeast Williopsis saturnus endophytic in maize roots was found to produce IAA and indole-3-pyruvic acid [20].…”

Section: Phytohormonesmentioning

confidence: 99%

Plant Bioactive Metabolites and Drugs Produced by Endophytic Fungi of Spermatophyta

2015

View full text Add to dashboard Cite

Abstract:It is known that plant-based ethnomedicine represented the foundation of modern pharmacology and that many pharmaceuticals are derived from compounds occurring in plant extracts. This track still stimulates a worldwide investigational activity aimed at identifying novel bioactive products of plant origin. However, the discovery that endophytic fungi are able to produce many plant-derived drugs has disclosed new horizons for their availability and production on a large scale by the pharmaceutical industry. In fact, following the path traced by the blockbuster drug taxol, an increasing number of valuable compounds originally characterized as secondary metabolites of plant species belonging to the Spermatophyta have been reported as fermentation products of endophytic fungal strains. Aspects concerning sources and bioactive properties of these compounds are reviewed in this paper.

show abstract

Section: Phytohormonesmentioning

confidence: 99%

Plant Bioactive Metabolites and Drugs Produced by Endophytic Fungi of Spermatophyta

2015

View full text Add to dashboard Cite

show abstract

“…The endophytic fungi were identified and found to belong to 9 taxa (Table 1), including the most commonly isolated endophytic genera such as Colletotrichum, Alternaria and Pestalotiopsis, of which most are known to produce various bioactive products (Lu et al, 2000;Li et al, 2001;Xiang et al, 2003). In contrast, some were rare endophytic genera such as Guignardia and Zythia, and these may be of potential practical value.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of antimicrobial activity of endophytic fungi from Camptotheca acuminata

Ding

Jiang²,

Zhou³

et al. 2010

Genet. Mol. Res.

View full text Add to dashboard Cite

ABSTRACT. Agricultural research of plant-derived endophytic fungi has grown in recent decades. We isolated 26 endophytic fungi from the leaves, stems and fruits of "the tree of life", Camptotheca acuminata, and tested them for antimicrobial activities based on growth inhibition measurements in a modified agar diffusion method. Fermentation broths from most of the isolates exhibited antifungal activity and 50% exhibited antibacterial activity; some of them also exhibited strong broad-spectrum antimicrobial activity. The strongest antimicrobial activity was exhibited by strains XSY10 and XSY15 against Rhizoctonia solani and Fusarium oxysporum f. sp. vasinfectum, with 75% and 67% inhibition, respectively. Strain XSJ01 gave strong activity against pathogenic bacteria, with inhibition zones more than 20 mm in diameter. The isolates were identified by molecular methods as belonging to nine taxa: Nigrospora, Diaporthe, Alternaria, Colletotrichum, Pestalotiopsis, Sordariomycete, Guignardiai, Penicillium, and Zythia. Based on 2105 ©FUNPEC-RP www.funpecrp.com.br Genetics and Molecular Research 9 (4): 2104-2112 (2010) Endophytic fungi of Camptotheca acuminata these results, we conclude that the endophytic fungi of C. acuminata are promising sources of novel bioactive compounds.

show abstract

“…De Artemisia mongolica foi isolado Colletotrichum gloeosporioides com as mesmas atividades acima citadas para Colletotrichum sp. Hong Lu et al, 2000). Coincidentemente, duas linhagens de Colletotrichum sp.…”

Section: Atividade Antibiótica Dos Metabólitos Extracelularesunclassified

Atividade antimicrobiana de fungos endofíticos isolados de plantas tóxicas da amazônia: Palicourea longiflora (aubl.) rich e Strychnos cogens bentham

et al. 2004

View full text Add to dashboard Cite

RESUMODas plantas tóxicas da Amazônia Palicourea longiflora e Strychnos cogens foram isolados 571 fungos endofíticos e 74 bactérias endofíticas. Palicourea longiflora (Rubiaceae) e outras espécies desse gênero estão relacionadas a 90% das mortes de gado na região Amazônica. Strychnos cogens (Loganiaceae) e outras espécies de Strychnos são utilizadas pelos indígenas na confecção de "curares". Entre os endófitos isolados de P. longiflora foram identificados os fungos: Colletotrichum sp. e seu telemorfo Glomerella sp., Guignardia sp., Aspergillus niger, Phomopsis sp. e Xylaria sp., além da bactéria Burkholderia gladioli, pertencente a um grupo de fixadoras de nitrogênio. Dos isolados de S. cogens foram identificados os fungos: Colletotrichum sp., Guignardia sp., Aspergillus niger e Trichoderma sp. Uma amostra de 79 isolados fúngicos teve seus metabólitos extracelulares bioensaiados contra microrganismos patogênicos e fitopatogênicos: 19 isolados inibiram um ou mais microrganismos-teste. Dos oito isolados com melhores resultados de inibição, as móleculas bioativas eram menores que 12.000 daltons, fato verificado pela diálise dos metabólitos. PALAVRAS-CHAVEPalicourea longiflora, Strychnos cogens, fungos endofíticos, bactérias endofíticas, bioensaios. Antimicrobial activity of endophytic fungi isolated from

show abstract

New bioactive metabolites produced by Colletotrichum sp., an endophytic fungus in Artemisia annua

Cited by 279 publications

References 15 publications

Plant Bioactive Metabolites and Drugs Produced by Endophytic Fungi of Spermatophyta

Plant Bioactive Metabolites and Drugs Produced by Endophytic Fungi of Spermatophyta

Evaluation of antimicrobial activity of endophytic fungi from Camptotheca acuminata

Atividade antimicrobiana de fungos endofíticos isolados de plantas tóxicas da amazônia: Palicourea longiflora (aubl.) rich e Strychnos cogens bentham

Contact Info

Product

Resources

About