Schiff base ligand (3-((4-mercaptophenyl)imino)-1-phenylindolin-2-one) of 1-phenylindoline-2,3-dione
and 4-aminothiophenol was synthesized by refluxing. Organotellurium(IV) complexes of type
(RTeCl3.NPhIATP and R2TeCl2.NPhIATP, where R = 4-hydroxyphenyl, 4-methoxyphenyl and
3-methyl-4-hydroxyphenyl, NPhIATP = Schiff base ligand). The ligand and its organotellurium(IV)
complexes (9a-f) were characterized by FT-IR, molar conductance, elemental analyses, UV-vis, mass,
1H & 13C NMR spectral studies. Geometry of all the compounds were optimized and octahedral geometry
have been proposed for all the tellurium(IV) complexes. Molecular docking was studied to find the
binding interactions between ligand (NPhIATP) and receptor proteins: E. coli (3t88) and S. aureus
(3ty7). The antimicrobial activity of ligand and its tellurium(IV) complexes have been screened against
bacteria and fungi. All the organotellurium(IV) complexes complexes showed good activity to ligand
towards different studied microorganisms.