New Antimicrobial Alkaloids from the Roots ofPolyalthia longifoliavar.pendula

Faizi, Shaheen; Khan, Rashid Ali; Azher, Soobia; Khan, Shakeel Ahmed; Tauseef, Saima; Ahmad, Aqeel

doi:10.1055/s-2003-38883

Cited by 78 publications

(61 citation statements)

References 14 publications

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“…According to Murthy et al (2005) and Nair et al (2009) P.longifolia leaves are economically important because it has demonstrated significant antibacterial, antifungal, anti viral and antioxidant activities. Pharmacological studies on the bark and leaves of the plants shows display effective antimicrobial activity (Faizi et al, 2003), cytotoxic function Chen et al, 2006), hypotensive effects (Saleem et al, 2005).…”

Section: Discussionmentioning

confidence: 99%

“…The therapeutic efficacy of P.longifolia extensively used in Indian system of medicine has been established through modern testing and evaluation in different disease conditions (Katkar, 2010). Reports on the plant has shown that its various parts possess different biological activities Pharmacologic studies on the bark and leaves of this plant show effective antimicrobial activity Faizi et al, 2003), cytotoxic function Chen et al, 2006), hypotensive effects (Saleem et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

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Effect of Dietary Inclusion of Polyalthia longifolia Leaf Meal as Phytobiotic Compared with Antibiotics on the Nutrient Retention, Immune Response and Serum Biochemistry of Broiler Chicken

Alagbe¹

2017

GJAS

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A 45-day feeding trial was conducted to evaluate the effect of dietary inclusion of Polyalthia longifolia leaf meal as phytobiotic compared with antibiotics on the nutrient retention, immune response and serum biochemistry of broiler chicks fed corn-soya meal diet. One hundred and fifty day old chick (Ross 308) of mixed sex was divided into five groups with three replicates, each of ten birds in a completely randomized design (CRD). Group 1was fed on basal diet without feed additives, group 2 was fed on basal diet supplemented with the antibiotic (Erythromycin) at 25mg/kg), group 3,4 and 5 were fed basal diets supplemented with Polyalthia longifolia leaf meal (PLM) at levels 1.5, 2.5 and 3.5% respectively. The basal diet was formulated to meet the nutritional requirements of growing birds according to NRC (1994), experimental parameters covered nutrient retention, immune response and some serum biochemical indices. The result revealed that there was a no significant (P>0.05) differences among all treatments in the values of protein retention, fat retention and the serum parameters measured. However, significant influences (P<0.05) were observed for fibre retention and the immune response of the birds to ND and IBD after vaccination. It can be concluded based on the data from the nutrient retention, immune response and those from serum biochemical parameters that PLM could be incorporated up to 3.5% level in the diet of broiler chickens.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effect of Dietary Inclusion of Polyalthia longifolia Leaf Meal as Phytobiotic Compared with Antibiotics on the Nutrient Retention, Immune Response and Serum Biochemistry of Broiler Chicken

Alagbe¹

2017

GJAS

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“…According to Katkar et al (2010), P. longifolia performs several functions such as antibacterial, antifungal, antidiabetic, antitumor, anti-ulcer, antioxidant and used in the treatment of the digestive system. Pharmacological studies on the bark and leaves of the plants shows display effective antimicrobial activity (Faizi et al, 2003), cytotoxic function Chen et al, 2006), hypotensive effects (Saleem et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

Untitled

2018

GJAS

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This experiment was carried out to investigate the effect of feeding different levels of Azolla pinnata, Polyalthia longifolia, Tithonia diversifolia, Moringa olifera, Azadirachta indica leaf meal infusion (PMNWA) as an organic supplement on the performance and nutrient retention of growing grass cutters. Experimental parameters covered growth performance and nutrient retention. Twenty, three weeks growing male grass cutters were randomly divided into five treatments groups with four replicates, each of one grass cutter in a Completely Randomized Design (CRD). Group 1 was fed basal diet without PMNWA, Group 2, 3, 4 and 5 were fed basal diets supplemented with PMNWA at levels of 5.00%, 10.0%, 15.0% and 20.0% respectively. The basal diet was formulated to meet the nutritional requirements of growing grass cutters according to Wogar (2011), the experiment lasted for 60 days and the results obtained showed that there were significant at P<0.05 differences among all treatments in the values of final live weight and feed conversion ratio . Results for feed intake, daily water intake and nutrient retention (protein, fibre and fat) were not significantly (P>0.05) affected with the inclusion of PMNWA. No mortality was recorded throughout the experimental period. Results obtained from this study showed that PMNWA is a good quality test materials with high contents of micro-nutrients which can improve the stability, palatability and shelf life of feed and its inclusion at 20.0% level does not have any deleterious effect on the general performance and health status of grass cutters.

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“…There are reports on the presence of numerous chemical constituents with interesting biological activities. For example, alkaloids pendulamine A and B isolated from the root extract exhibited significant antibacterial activities 14 while flavonoids and their glycosides isolated from leaves possess free radical scavenging ability 15 .…”

Section: Introductionmentioning

confidence: 99%