New Access to Pseudo-ionones andPseudo-iso-methyl Ionones from Geranyl Derivatives

Abstract

Pseudo-ionones and pseudo-iso-methyl ionones, precursors of fragrant derivatives were obtained from geranyl chloride, an industrially available starting material.

Synthesis of apo-13- and apo-15-lycopenoids, cleavage products of lycopene that are retinoic acid antagonists

“…Starting with the inexpensive ($0.50 per gram) commercially available trans alcohol, geraniol (11), we have smoothly prepared 9. A somewhat related approach to 10 starting from the more expensive geranyl chloride (approximately $12 per gram) and utilizing pyrolysis of -sulfinyl carbonyl compounds has been reported (33). More importantly, the procedure described here proceeds in fewer operationally easier steps (one vs. four), with comparable or better yields.…”