Nevus comedonicus syndrome

Abstract

A case of nevus comedonicus syndrome with atypical cutaneous presentation (widespread involvement without any particular pattern, midline lesions involving lower abdomen and involvement of bilateral pinna), and some unusual skeletal (adduction deformity involving bilateral metatarsal along with medial deviation at the level of tarsometatarsal joint), central nervous system (agenesis of corpus callosum with a interhemispheric cyst), visceral (pancreatic cyst) and neurological manifestations have been illustrated.

Further delineation of the phenotypic spectrum of nevus comedonicus syndrome to include congenital pulmonary airway malformation of the lung and aneurysm

“… Note : Search details included: (“naevus”[All Fields] OR “nevus, pigmented”[MeSH Terms] OR (“nevus”[All Fields] AND “pigmented”[All Fields]) OR “pigmented nevus”[All Fields] OR “nevus”[All Fields] OR “nevus”[MeSH Terms]) AND comedonicus[All Fields] AND (“syndrome”[MeSH Terms] OR “syndrome”[All Fields]). References: (Kaliyadan, Nampoothiri, Sunitha, & Kuruvilla, ; Patrizi, Neri, Fiorentini, & Marzaduri, ; Pavithra, Pai, Mallya, & Pai, ; Ferrari et al, ; Suite and Mahabir, ; Seo, Piao, Suhr, Lee, & Park, ; Yadav, Mendiratta, Rana, & Chander, ; Qian, Liu, Zhou, & Zhang, ; Engber, , ; Whyte, ; Ghelbazouri et al, ; Alpsoy, Durusoy, Ozbilim, Karpuzoğlu, & Yilmaz, ; Ito, Mitamura, Tsuji, Harada, & Urabe, ; Vidaurri‐de la Cruz, Tamayo‐Sánchez, Durán‐McKinster, de la Luz Orozco‐Covarrubias, & Ruiz‐Maldonado, ; Martinez, Levrero, Bazzano, Larre Borges, & De Anda, ; Filosa, Bugatti, Ciattaglia, Salaffi, & Carotti, ). NC has been seen in patients with dual diagnoses such as orofacial digital syndrome (Baker & Agim, ) and Alagille syndrome (Woods, Larcher, & Harper, ).…”

Blackheads in the forearm: a case of nevus comedonicus

“…The most common symptoms of this neurocutaneous syndrome include cataracts, scoliosis, fused vertebrae, spina bifida, and delayed mental development [5,7,8].…”

“…NC can be associated with skeletal, ocular, and central nervous system abnormalities in the context of nevus comedonicus syndrome (NCS) [5,7].…”

Nevus Comedonicus: Case Report

“…It features bundles of papules and dilated follicular openings containing epidermal residues and firm pigmented horny plugs, similar to comedones [ 4 ]. The lesions typically present a linear or zosteriform distribution, but extensive areas have already been described, including with bilateral involvement [ 5 ]. The most frequently affected sites are the face, trunk, neck, and upper limbs.…”