Neutron diffraction investigations of l- and d-alanine at different temperatures: the search for structural evidence for parity violation

Wilson, Chick C.; Myles, Dean A. A.; Ghosh, Minakshi; Johnson, L.N.; Wang, Wenging

doi:10.1039/b419295h

Cited by 78 publications

(64 citation statements)

References 28 publications

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“…This physical observation puts L-leucine in the same class of L-valine crystal among the aliphatic amino acid crystals which present at least one type of structural change. In another class it is possible to find L-alanine [6], D-alanine [21], D-valine [22] and L-isoleucine [8], which are stable under a very large range of temperature (at least for low-temperature conditions).…”

Section: Discussionmentioning

confidence: 99%

High temperature Raman spectra of L-leucine crystals

Filho¹,

Freire²,

Lima³

et al. 2008

Braz. J. Phys.

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Single crystal samples of L-leucine, C 6 H 13 NO 2 , a fundamental aliphatic amino acid of the human body, have been studied by Raman spectroscopy at temperatures from 300 to 430 K over the spectral range from 50 to 3100 cm −1 . A tentative assignment of all bands is given. For high temperatures, several modifications on the Raman spectra were observed at about 353 K, giving evidence that the L-leucine crystal undergoes a structural phase transition. An interpretation for this phase transition in terms of group theory analysis is given.

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Section: Discussionmentioning

confidence: 99%

High temperature Raman spectra of L-leucine crystals

Filho¹,

Freire²,

Lima³

et al. 2008

Braz. J. Phys.

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“…However, regardless of a pair of enantiopure (S)-and (R)-alcohols, we are aware that CD profiles (wavelength extrema and absolute magnitude) are exactly in non-mirror-image relation, although we did not mention this subtle difference in the original paper [121]. This non-mirror-image relation may be ascribed to some impurities, as claimed in several papers [68,71,73,117]. It may also infer other unknown reasons, such as an inherent mirror symmetry breaking at a global level upward, our universe scale [123,124] and macroscopic MPV effects [21,37,43,46,51,67,72,74].…”

Section: Optically Active Polymer Aggregates In the Ground Statementioning

confidence: 89%

“…Although it is already established that left-right symmetry is definitively broken at the elemental particle, subatomic and atomic levels [52][53][54][55][56][57][58][59][60][61][62][63][64][65][66], the detection of dissymmetry at the molecular level, so-called molecular parity violation (MPV), remains an unsolved issue. It is much debated whether the MPV hypothesis is valid and, even if it is true, whether it is detectable spectroscopically or by other acceptable methods [67][68][69][70][71][72][73][74][75][76].…”

Section: Introductionmentioning

confidence: 99%

Supramolecular Chirality: Solvent Chirality Transfer in Molecular Chemistry and Polymer Chemistry

Fujiki

2014

Symmetry

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Controlled mirror symmetry breaking arising from chemical and physical origin is currently one of the hottest issues in the field of supramolecular chirality. The dynamic twisting abilities of solvent molecules are often ignored and unknown, although the targeted molecules and polymers in a fluid solution are surrounded by solvent molecules. We should pay more attention to the facts that mostly all of the chemical and physical properties of these molecules and polymers in the ground and photoexcited states are significantly influenced by the surrounding solvent molecules with much conformational freedom through non-covalent supramolecular interactions between these substances and solvent molecules. This review highlights a series of studies that include: (i) historical background, covering chiral NaClO 3 crystallization in the presence of D-sugars in the late 19th century; (ii) early solvent chirality effects for optically inactive chromophores/fluorophores in the 1960s-1980s; and (iii) the recent development of mirror symmetry breaking from the corresponding achiral or optically inactive molecules and polymers with the help of molecular chirality as the solvent use quantity.

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“…DL-alanine itself does not show any phase transitions with increasing pressure [56]. The molecules are linked via the NH … O hydrogen bonds in a three-dimensional framework [57,58], the CH 3 À side chains do not form any hydrogen bonds, similarly to the structure of L-alanine [59][60][61][62], and their rotation does not result in any phase transitions either in L- [63][64][65], or in DL-alanine [56]. In contrast to that, DL-alaninium semi-oxalate monohydrate, in which this homomolecular framework is broken, undergoes a single-crystal to single-crystal phase transition at a pressure between 1.5 and 2.4 GPa [55].…”

Section: Structure Destabilization By the Second Componentmentioning

confidence: 99%

Multicomponent organic crystals at high pressure

Boldyreva

2014

Zeitschrift Für Kristallographie Crystalline Materials

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High-pressure research of the crystals of organic and coordination compounds is now a well-established field. However, the studies of multicomponent crystals (hydrates, solvates, salts and co-crystals) are just emerging. The aim of this paper is to give a personal view of what makes the multicomponent organic systems peculiar for high-pressure research as compared with the monocomponent ones. Several different types of structure response to compression and reverse decompression are reviewed with examples based on research of salts, co-crystals and hydrates of amino acids. Challenges and prospects of further studies are discussed.

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Neutron diffraction investigations of l- and d-alanine at different temperatures: the search for structural evidence for parity violation

Cited by 78 publications

References 28 publications

High temperature Raman spectra of L-leucine crystals

High temperature Raman spectra of L-leucine crystals

Supramolecular Chirality: Solvent Chirality Transfer in Molecular Chemistry and Polymer Chemistry

Multicomponent organic crystals at high pressure

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