Abstract:Background: Selective tropomyosin receptor kinase (Trk) inhibitors are known to provide promising outcomes in selected tumor patients with neurotrophic tyrosine receptor kinase (NTRK) gene fusions. In the present study, we aimed to determine whether there was a NTRK1 and NTRK2 expression in cervical squamous cell carcinoma (SCC) and precursor lesions. Materials and methods: A total of 92 formalin-fixed paraffin-embedded tissue samples of cervical SCC, squamous intraepithelial lesion (SIL) and non-neoplastic ce… Show more
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