Neurotoxicity of Contrast Agents

Feingold, Alfred

doi:10.1097/00000542-199505000-00034

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Neurotoxizität1

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“…Aufgrund der Hydrophilie der KM besteht eine gute neurale Verträglichkeit, da die Blut-Hirnschranke kaum überschritten wird [32,33]. Es liegen allerdings Fallberichte von KM assoziierter Hyperagitation, Hyperventilation und subarachnoidaler Blutung vor [34,35].…”

Section: Neurotoxizitätunclassified

Intravenöse Anwendung von jodiertem, nichtionischem, nieder- bis isoosmolarem Kontrastmittel: Sicherheitsaspekte

Metz-Schimmerl¹,

Metz²,

Domanovits

et al. 2002

Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr

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It is the purpose of this review to provide information about the safe use of intravenously administered, iodinated, non-ionic, low or isoosmolar contrast media for radiological examinations, how to avoid adverse events, and how to react professionally in case of an anaphylactic reaction. Methods of prophylaxis and therapy for anaphylactic and chemotoxic effects of contrast media administration as well as absolute and relative contraindications are discussed. Medico-legal considerations of contrast agent administration, informed consent of patients, and methods of risk management for undesired contrast media reactions are considered in this article. Establishment of adminstration standards for contrast media is of tremendous importance to standardize radiological procedures. This basic radiological documentation is part of the institutional and individual legal safety management.

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