“…SOD is the enzyme that catalyze and H + to less toxic H 2 O 2 and O 2 while CAT converts H 2 O 2 into H 2 O ( Maharajan et al, 2018 ), thus to prevent oxidative stress and maintain cell homeostasis ( Mansour and Mossa, 2009 ). Therefore, the SOD-CAT system provide the first line of defense against ROS damage in organisms ( Liu et al, 2015 ). Previous research suggested that the activity of SOD could be activated to dispel the increased ROS in cells ( Zhao et al, 2013 ).…”
Early life stages of marine organisms are the most sensitive stages to environment stressors including pollutants. In order to understand the toxicological effects induced by MeHg exposure on juveniles of large yellow croaker (Pseudosciaena crocea), a toxicity test was performed wherein fish were exposed to sub-lethal concentrations of MeHg under laboratory conditions (18 ± 1°C; 26 ± 1 in salinity). After 30 days of 0–4.0 μg L-1 MeHg exposure, SOD activity was significantly decreased in the 0.25, 1.0, and 4.0 μg L-1 treatments; while CAT activity was significantly increased in the 4.0 μg L-1 treatments; GSH level, GPx activity were significantly elevated in the 4.0 μg L-1 treatments, respectively. Meanwhile, malondialdehyde content was also significantly increased in the 1.0 and 4.0 μg L-1 treatments with respect to the control. Acetylcholinesterase activity was significantly decreased by 18.3, 25.2, and 21.7% in the 0.25, 1.0, and 4.0 μg L-1 treatments, respectively. The expression of TCTP, GST3, Hsp70, Hsp27 mRNA were all up-regulated in juveniles with a dose-dependent manner exposed to MeHg. These results suggest that large yellow croaker juveniles have the potential to regulate the levels of antioxidant enzymes and initiate immune response in order to protect fish to some extent from oxidative stress induced by MeHg.
“…SOD is the enzyme that catalyze and H + to less toxic H 2 O 2 and O 2 while CAT converts H 2 O 2 into H 2 O ( Maharajan et al, 2018 ), thus to prevent oxidative stress and maintain cell homeostasis ( Mansour and Mossa, 2009 ). Therefore, the SOD-CAT system provide the first line of defense against ROS damage in organisms ( Liu et al, 2015 ). Previous research suggested that the activity of SOD could be activated to dispel the increased ROS in cells ( Zhao et al, 2013 ).…”
Early life stages of marine organisms are the most sensitive stages to environment stressors including pollutants. In order to understand the toxicological effects induced by MeHg exposure on juveniles of large yellow croaker (Pseudosciaena crocea), a toxicity test was performed wherein fish were exposed to sub-lethal concentrations of MeHg under laboratory conditions (18 ± 1°C; 26 ± 1 in salinity). After 30 days of 0–4.0 μg L-1 MeHg exposure, SOD activity was significantly decreased in the 0.25, 1.0, and 4.0 μg L-1 treatments; while CAT activity was significantly increased in the 4.0 μg L-1 treatments; GSH level, GPx activity were significantly elevated in the 4.0 μg L-1 treatments, respectively. Meanwhile, malondialdehyde content was also significantly increased in the 1.0 and 4.0 μg L-1 treatments with respect to the control. Acetylcholinesterase activity was significantly decreased by 18.3, 25.2, and 21.7% in the 0.25, 1.0, and 4.0 μg L-1 treatments, respectively. The expression of TCTP, GST3, Hsp70, Hsp27 mRNA were all up-regulated in juveniles with a dose-dependent manner exposed to MeHg. These results suggest that large yellow croaker juveniles have the potential to regulate the levels of antioxidant enzymes and initiate immune response in order to protect fish to some extent from oxidative stress induced by MeHg.
“…Fertilizer and crop protection use for large-scale agricultural activities has long been at the centre of a vigorous debate. A number of academic studies across disciplines have debated their effects on public health and the environment along with how to effectively control their use [57][58][59][60][61][62][63]; outside academic contexts, European Union policymakers and legislators voted in April 2018 an almost complete ban on neonicotinoids due to their effects on honeybees and other pollinators. This motivates our idea of assessing whether the effect of agricultural inputs on maximal wheat yield levels can be identified.…”
Wheat farming provides 28.5% of global cereal production. After steady growth in average crop yield from 1950 to 1990, wheat yields have generally stagnated, which prompts the question of whether further improvements are possible. Statistical studies of agronomic parameters such as crop yield have so far exclusively focused on estimating parameters describing the whole of the data, rather than the highest yields specifically. These indicators include the mean or median yield of a crop, or finding the combinations of agronomic traits that are correlated with increasing average yields. In this paper, we take an alternative approach and consider high yields only. We carry out an extreme value analysis of winter wheat yield data collected in England and Wales between 2006 and 2015. This analysis suggests that, under current climate and growing conditions, there is indeed a finite upper bound for winter wheat yield, whose value we estimate to be 17.60 tonnes per hectare. We then refine the analysis for strata defined by either location or level of use of agricultural inputs. We find that there is no statistical evidence for variation of maximal yield depending on location, and neither is there statistical evidence that maximum yield levels are improved by high levels of crop protection and fertilizer use.
“…Ansari ve Ansari (2014) Zebra balığı üzerine organofosforlu bir böcek öldürücü dimetoat uygulamışlar ve sonuç olarak bu kimyasala maruz kalan balıkların CAT seviyelerinde bir azalmaya neden olduğunu solungaçlarında GSH düzeylerinin yine azaldığını ve LPO seviyelerinin ise arttığını ifade etmişlerdir (Ansari and Ansari, 2014a). Liu et al (2015) Japon balığı üzerine uygulamış oldukları organofosforlu böcek ilacı Triazophosun etkilerine bakmış ve sonuç olarak GSH, SOD, CAT ve laktat dehidrogenaz (LDH) aktivitelerinin azaldığını açıklamışlardır (Liu et al, 2015). Ahmet ve Nasr (2015) erkek albino sıçanlar üzerinde uygulamış oldukları brokoli su ekstraktı, ferulik asit ve imidaklopridinin oksidatif stres üzerine sonuçlarını araştırmışlar ve imidaklopridinin, LPO içeriklerini artırdığını, Brokoli ve ferulik asit LPO seviyesini azalttığını, imidaklopridin GSH'yı düşürmüş, brokoli ve ferulik asit birlikte kullanıldığı zaman ise GSH düzeyini iyileştirdiğini açıklamışlardır (Ahmed and Nasr, 2015).…”
Bu çalışmada, Kars Çayından yakalanan Capoeta capoeta (Guldenstaedt 1773) üzerine Lambda cyhalothrin (LCT)'in etkilerinin biyokimyasal ve moleküler yöntemlerle araştırılması amaçlandı. Kars Çayından yakalanan balıklar her grupta 10 adet balık olacak şekilde 3 gruba ayrıldı. Gruplar; kontrol grubu (herhangi bir uygulama yapılmadı), I. gruptaki balıklar 0.012 μgL-1 LCT içeren tankta, II. gruptaki balıklar ise 0.025 μgL-1 LCT içeren tankta 6 saat süreyle bekletildi. Bu süre sonunda balıklardan biyokimyasal ve moleküler analizler için kan ve karaciğer doku örnekleri alındı. Uygulanan spektrofotometrik analizlarin sonucu olarak Glutatyon (GSH) düzeyleri için kontrol ve uygulama gruplarında istatistiksel farklılık saptanmadı (P>0.05). 8-Hidroksi-2'-Deoksiguanozin (8-OHdG) düzeylerinin ise LCT uygulanan gruplarda kontrol grubuna göre azaldığı tespit edildi (P<0.01). Karaciğer Glutatyon S-transferaz (GST), Glutatyon peroksidaz (GPx), Glutatyon Redüktaz (GR), Katalaz (CAT) ve Süperoksit Dismutaz (SOD) enzimlerinin ekspresyon seviyeleri RT-PCR yöntemi ile araştırıldığında ise kontrol grubuna göre artış meydana geldiği belirlendi. Sonuç olarak; LCT'in Capoeta capoeta balık türleri üzerinde toksik etki gösterdiği, buna bağlı olarak balıklarda antioksidan enzim düzeyleri artarak oksidatif hasarı ve DNA/RNA hasarını azalttığı tespit edildi.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.