Neurotized free <scp>VRAM</scp> used to create myoelectric signals in a muscle‐depleted area for targeted muscle reinnervation for intuitive prosthesis control: A case report

Background: It is estimated that by 2050, a total of 3.6 million patients will be living with an amputation in the United States. The objective of this systematic review is to evaluate the effect of targeted muscle reinnervation (TMR) on pain and physical functioning in amputees. Methods: A literature search was performed on PubMed, Embase, and MEDLINE up to November 28, 2021. Clinical studies assessing the outcomes of TMR (pain, prosthesis control, life quality, limb function, and disability) were included. Results: Thirty-nine articles were included. The total number of patients who underwent TMR was 449, and 716 were controls. Mean follow-up was 25 months. A total of 309 (66%) lower-limb and 159 (34%) upper-limb amputations took place in the TMR group, the most common being below-knee amputations (39%). The control group included a total of 557 (84%) lower-limb and 108 (16%) upper-limb amputations; the greatest proportion being below-knee amputations in this group as well (54%). Trauma was the most common indication for amputation. Phantom limb pain scores were lower by 10.2 points for intensity (P = 0.01), 4.67 points for behavior (P = 0.01), and 8.9 points for interference (P = 0.09). Similarly, residual limb pain measures were lower for cases for intensity, behavior, and interference, but they failed to reach significance. Neuroma symptoms occurred less frequently, and functional and prosthesis control outcomes improved following TMR. Conclusion: The literature evidence suggests that TMR is a promising therapy for improving pain, prosthesis use, and functional outcomes after limb amputation.

show abstract

“…Outcome measures were divided into pain, functional, and electrical measures, and definitions are presented in Table 1. 1–83…”

Section: Methodsmentioning

confidence: 99%

Pain and Functional Outcomes following Targeted Muscle Reinnervation: A Systematic Review

ElAbd¹,

Dow²,

Jabori³

et al. 2023

Plastic &Amp; Reconstructive Surgery

View full text Add to dashboard Cite

show abstract

Bringing the Below-Knee amputation out of the Civil War era: Utilization of the neurovascularized lateral compartment flap, TMR, and RPNI

Bascone

Sulkar

McGraw

et al. 2023

Orthoplastic Surgery

View full text Add to dashboard Cite

Challenges and Potential in Targeted Muscle Reinnervation in Pediatric Amputees

et al. 2021

View full text Add to dashboard Cite

Targeted muscle reinnervation (TMR) is a powerful new tool in preventing and treating residual limb and phantom limb pain. In the adult population, TMR is rapidly becoming standard of care; however, there is a paucity of literature regarding indications and outcomes of TMR in the pediatric population. We present 2 cases of pediatric patients who sustained amputations and the relevant challenges associated with TMR in their cases. One is a 7-year-old patient who developed severe phantom and residual limb pain after a posttraumatic above-knee amputation. He failed pharmacologic measures and underwent TMR. He obtained complete relief of his symptoms and is continuing to do well 1.5 years postoperatively. The other is a 2-year-old boy with bilateral wrist and below-knee amputations as sequelae of sepsis. TMR was not performed because the patient never demonstrated evidence of phantom limb pain or symptomatic neuroma formation. We use these 2 cases to explore the challenges particular to pediatric patients when considering treatment with TMR, including capacity to report pain, risks of anesthesia, and cortical plasticity. These issues will be critical in determining how TMR will be applied to pediatric patients.

show abstract

Neurotized free VRAM used to create myoelectric signals in a muscle‐depleted area for targeted muscle reinnervation for intuitive prosthesis control: A case report

Cited by 3 publications

References 14 publications

Pain and Functional Outcomes following Targeted Muscle Reinnervation: A Systematic Review

Pain and Functional Outcomes following Targeted Muscle Reinnervation: A Systematic Review

Bringing the Below-Knee amputation out of the Civil War era: Utilization of the neurovascularized lateral compartment flap, TMR, and RPNI

Challenges and Potential in Targeted Muscle Reinnervation in Pediatric Amputees

Contact Info

Product

Resources

About